Chinese Journal of Polymer Science

, Volume 36, Issue 5, pp 604–611 | Cite as

Comparative Studies on Hydrophilic and Hydrophobic Segments Grafted Poly(vinyl chloride)

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Abstract

Poly(vinyl chloride) (PVC) is one of the mostly produced plastics in the world and is widely used in single-use medical devices. However, the additives that are often necessary for PVC arouse concerns of its safety, thus quests the modifications of PVC itself. In this study, poly(ethylene glycol) (PEG) and polydimethylsiloxane (PDMS) segments were grafted onto PVC backbone in similar ways, and the chemical structures of the modified PVCs were characterized by Fourier transform infrared spectra, X-ray photoelectron spectra, thermogravimetric analysis and differential scanning calorimetry. Moreover, the water contact angle, protein adsorption, platelet adhesion, cell attachment and proliferation on different material surfaces were studied and compared. It was found that both PEG and PDMS grafting yielded improvement on biocompatibility compared with bare PVC, while hydrophobic PDMS grafted PVC showed more effective on cell attachment and proliferation than that of hydrophilic PEG grafted PVC.

Keywords

Poly(vinyl chloride) Poly(ethylene glycol) Polydimethylsiloxane Grafting Biomedical properties 

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Notes

Acknowledgments

This work was financially supported by the National Natural Science Foundation of China (No. 81671792), National Key R&D program of China (No. 2016YFC0104100), and the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).

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Copyright information

© Chinese Chemical Society, Institute of Chemistry, Chinese Academy of Sciences and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Yan Zhang
    • 1
  • Zi-Peng Yuan
    • 1
  • Yu Qin
    • 1
  • Ji Dai
    • 1
  • Tao Zhang
    • 1
  1. 1.Department of Biomedical Engineering, College of Engineering and Applied SciencesNanjing UniversityNanjingChina

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