Chinese Journal of Polymer Science

, Volume 32, Issue 7, pp 864–870 | Cite as

Fabrication of highly porous interconnected three-dimensional scaffolds with micro-channels

  • Zhi-xiang Cui
  • Hai-bin Zhao
  • Yi-yan Peng
  • Yottha Srithep
  • Lih-Sheng Turng
  • Chang-yu Shen (申长雨)
Papers
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Abstract

A novel highly porous 3-D poly(ɛ-caprolactone) (PCL) scaffold with micro-channels was fabricated by injection molding and diluent acetic acids leaching technologies. In this study, the chitosan fiber was employed to form the microchannel in PCL matrix. The morphology, porosity and mechanical properties of the scaffolds were studied and calculated. It was found that the larger the content of chitosan fiber is, the higher the porosity would be, due to the volumetric expansion of chitosan fiber in PCL matrix during it being leached. In addition, the less the content of chitosan fiber is, the higher the compressive modulus would be.

Keywords

Injection molding Micro-channel Chitosan fiber Poly(ɛ-caprolactone) scaffold 
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Copyright information

© Chinese Chemical Society, Institute of Chemistry, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Zhi-xiang Cui
    • 1
  • Hai-bin Zhao
    • 2
  • Yi-yan Peng
    • 3
  • Yottha Srithep
    • 3
  • Lih-Sheng Turng
    • 3
  • Chang-yu Shen (申长雨)
    • 4
  1. 1.Fujian University of TechnologyFuzhouChina
  2. 2.Shandong UniversityJinanChina
  3. 3.University of Wisconsin-MadisonMadisonUSA
  4. 4.Zhengzhou UniversityZhengzhouChina

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