Knowledge and Information Systems

, Volume 50, Issue 1, pp 117–143 | Cite as

Clinical evidence framework for Bayesian networks

  • Barbaros YetEmail author
  • Zane B. Perkins
  • Nigel R. M. Tai
  • D. William R. Marsh
Regular Paper


There is poor uptake of prognostic decision support models by clinicians regardless of their accuracy. There is evidence that this results from doubts about the basis of the model as the evidence behind clinical models is often not clear to anyone other than their developers. In this paper, we propose a framework for representing the evidence-base of a Bayesian network (BN) decision support model. The aim of this evidence framework is to be able to present all the clinical evidence alongside the BN itself. The evidence framework is capable of presenting supporting and conflicting evidence, and evidence associated with relevant but excluded factors. It also allows the completeness of the evidence to be queried. We illustrate this framework using a BN that has been previously developed to predict acute traumatic coagulopathy, a potentially fatal disorder of blood clotting, at early stages of trauma care.


Bayesian networks Evidence-based medicine Prognostic models Clinical decision support Knowledge engineering 



This research has been partly funded by the Academic Department of Military Surgery and Trauma, UK Defence Medical Services, and a Principal’s Studentship, Queen Mary University of London.


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Copyright information

© Springer-Verlag London 2016

Authors and Affiliations

  1. 1.School of Electronic Engineering and Computer ScienceQueen Mary University of LondonLondonUK
  2. 2.Centre for Trauma ScienceQueen Mary University of LondonLondonUK
  3. 3.The Royal London HospitalLondonUK
  4. 4.Department of Industrial EngineeringHacettepe UniversityAnkaraTurkey

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