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Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis

Abstract

Researches have been performed to investigate the effects of phototherapy on improving performance and reduction of muscular fatigue. However, a great variability in the light parameters and protocols of the trials are a concern to establish the efficacy of this therapy to be used in sports or clinic. The aim of this study is to investigate the effectiveness, moment of application of phototherapy within an exercise protocol, and which are the parameters optimally effective for the improvement of muscular performance and the reduction of muscular fatigue in healthy people. Systematic searches of PubMed, PEDro, Cochrane Library, EMBASE, and Web of Science databases were conducted for randomized clinical trials to March 2017. Analyses of risk of bias and quality of evidence of the included trials were performed, and authors were contacted to obtain any missing or unclear information. We included 39 trials (861 participants). Data were reported descriptively through tables, and 28 trials were included in meta-analysis comparing outcomes to placebo. Meta-analysis was performed for the variables: time until reach exhaustion, number of repetitions, isometric peak torque, and blood lactate levels showing a very low to moderate quality of evidence and some effect in favor to phototherapy. Further investigation is required due the lack of methodological quality, small sample size, great variability of exercise protocols, and phototherapy parameters. In general, positive results were found using both low-level laser therapy and light-emitting diode therapy or combination of both in a wavelength range from 655 to 950 nm. Most of positive results were observed with an energy dose range from 20 to 60 J for small muscular groups and 60 to 300 J for large muscular groups and maximal power output of 200 mW per diode.

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References

  1. 1.

    Saw AE, Main LC, Gastin PB (2016) Monitoring the athlete training response: subjective self-reported measures trump commonly used objective measures: a systematic review. Br J Sports Med 50(5):281–291. https://doi.org/10.1136/bjsports-2015-094758

  2. 2.

    van Reijen M, Vriend I, van Mechelen W, Finch CF, Verhagen EA (2016) Compliance with sport injury prevention interventions in randomised controlled trials: a systematic review. Sports Med. https://doi.org/10.1007/s40279-016-0470-8

  3. 3.

    Nakhostin Ansari N, Naghdi S, Karimi H, Fakhari Z, Hasson S (2016) A randomized controlled pilot study to investigate the effect of whole body vibration on lower extremity fatigue. J Sport Rehabil. https://doi.org/10.1123/jsr.2015-0202

  4. 4.

    Engel FA, Holmberg HC, Sperlich B (2016) Is there evidence that runners can benefit from wearing compression clothing? Sports Med. https://doi.org/10.1007/s40279-016-0546-5

  5. 5.

    LaBella CR, Huxford MR, Grissom J, Kim KY, Peng J, Christoffel KK (2011) Effect of neuromuscular warm-up on injuries in female soccer and basketball athletes in urban public high schools: cluster randomized controlled trial. Arch Pediatr Adolesc Med 165(11):1033–1040. https://doi.org/10.1001/archpediatrics.2011.168

  6. 6.

    Machado AF, Ferreira PH, Micheletti JK, de Almeida AC, Lemes IR, Vanderlei FM et al (2016) Can water temperature and immersion time influence the effect of cold water immersion on muscle soreness? A systematic review and meta-analysis. Sports Med 46(4):503–514. https://doi.org/10.1007/s40279-015-0431-7

  7. 7.

    Weerapong P, Hume PA, Kolt GS (2005) The mechanisms of massage and effects on performance, muscle recovery and injury prevention. Sports Med 35(3):235–256

  8. 8.

    Calleja-Gonzalez J, Terrados N, Mielgo-Ayuso J, Delextrat A, Jukic I, Vaquera A et al (2016) Evidence-based post-exercise recovery strategies in basketball. Phys Sportsmed 44(1):74–78. https://doi.org/10.1080/00913847.2016.1102033

  9. 9.

    Barnett A (2006) Using recovery modalities between training sessions in elite athletes: does it help? Sports Med 36(9):781–796

  10. 10.

    Borsa PA, Larkin KA, True JM (2013) Does phototherapy enhance skeletal muscle contractile function and postexercise recovery? A systematic review. J Athl Train 48(1):57–67. https://doi.org/10.4085/1062-6050-48.1.12

  11. 11.

    Leal-Junior ECP, Vanin AA, Miranda EF, de Carvalho Pde T, Dal Corso S, Bjordal JM (2015) Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis. Lasers Med Sci 30(2):925–939. https://doi.org/10.1007/s10103-013-1465-4

  12. 12.

    Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR (2012) The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng 40(2):516–533. https://doi.org/10.1007/s10439-011-0454-7

  13. 13.

    Huang YY, Sharma SK, Carroll J, Hamblin MR (2011) Biphasic dose response in low level light therapy - an update. Dose-response 9(4):602–618. https://doi.org/10.2203/dose-response.11-009.Hamblin

  14. 14.

    Antonialli FC, De Marchi T, Tomazoni SS, Vanin AA, dos Santos Grandinetti V, de Paiva PR et al (2014) Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes. Lasers Med Sci 29(6):1967–1976. https://doi.org/10.1007/s10103-014-1611-7

  15. 15.

    Albuquerque-Pontes GM, Vieira RP, Tomazoni SS, Caires CO, Nemeth V, Vanin AA et al (2014) Effect of pre-irradiation with different doses, wavelengths, and application intervals of low-level laser therapy on cytochrome c oxidase activity in intact skeletal muscle of rats. Lasers Med Sci 30:59–66. https://doi.org/10.1007/s10103-014-1616-2

  16. 16.

    Houreld NN, Masha RT, Abrahamse H (2012) Low-intensity laser irradiation at 660 nm stimulates cytochrome c oxidase in stressed fibroblast cells. Lasers Surg Med 44(5):429–434. https://doi.org/10.1002/lsm.22027

  17. 17.

    De Marchi T, Schmitt VM, Machado GP, de Sene JS, de Col CD, Tairova O et al (2017) Does photobiomodulation therapy is better than cryotherapy in muscle recovery after a high-intensity exercise? A randomized, double-blind, placebo-controlled clinical trial. Lasers Med Sci 32(2):429–437. https://doi.org/10.1007/s10103-016-2139-9

  18. 18.

    de Paiva PR, Tomazoni SS, Johnson DS, Vanin AA, Albuquerque-Pontes GM, Machado CD et al (2016) Photobiomodulation therapy (PBMT) and/or cryotherapy in skeletal muscle restitution, what is better? A randomized, double-blinded, placebo-controlled clinical trial. Lasers Med Sci 31(9):1925–1933. https://doi.org/10.1007/s10103-016-2071-z

  19. 19.

    de Souza CG, Borges DT, de Brito Macedo L, Brasileiro JS (2016) Low-level laser therapy reduces the fatigue index in the ankle plantar flexors of healthy subjects. Lasers Med Sci 31(9):1949–1955. https://doi.org/10.1007/s10103-016-2074-9

  20. 20.

    Miranda EF, Vanin AA, Tomazoni SS, Grandinetti VD, de Paiva PR, Machado CD et al (2016) Using pre-exercise photobiomodulation therapy combining super-pulsed lasers and light-emitting diodes to improve performance in progressive cardiopulmonary exercise tests. J Athl Train. https://doi.org/10.4085/1062-6050-51.3.10

  21. 21.

    Machado AF, Micheletti JK, Vanderlei FM, Nakamura FY, Leal Junior ECP, Netto Junior J et al (2017) Effect of low-level laser therapy (LLLT) and light-emitting diodes (LEDT) applied during combined training on performance and post-exercise recovery: protocol for a randomized placebo-controlled trial. Braz J Phys Ther 21(4):296–304. https://doi.org/10.1016/j.bjpt.2017.05.010

  22. 22.

    Higgins JPT, Green S (2011) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration. Available from http://www.handbook.cochrane.org

  23. 23.

    Balshem H, Helfand M, Schunemann HJ, Oxman AD, Kunz R, Brozek J et al (2011) GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol 64(4):401–406. https://doi.org/10.1016/j.jclinepi.2010.07.015

  24. 24.

    Almeida P, Lopes-Martins RA, De Marchi T, Tomazoni SS, Albertini R, Correa JC et al (2012) Red (660 nm) and infrared (830 nm) low-level laser therapy in skeletal muscle fatigue in humans: what is better? Lasers Med Sci 27(2):453–458. https://doi.org/10.1007/s10103-011-0957-3

  25. 25.

    da Silva Alves MA, Pinfildi CE, Neto LN, Lourenço RP, de Azevedo PHSM, Dourado VZ et al (2014) Acute effects of low-level laser therapy on physiologic and electromyographic responses to the cardiopulmonary exercise testing in healthy untrained adults. Lasers Med Sci 29:1945–1951. https://doi.org/10.1007/s10103-014-1595-3

  26. 26.

    Baroni BM, Leal Junior EC, Marchi T, Lopes AL, Salvador M, Vaz MA (2010) Low level laser therapy before eccentric exercise reduces muscle damage markers in humans. Eur J Appl Physiol. https://doi.org/10.1007/s00421-010-1562-z

  27. 27.

    Baroni BM, Leal Junior ECP, Geremia JM, Diefenthaeler F, Vaz MA (2010) Effect of light-emitting diodes therapy (LEDT) on knee extensor muscle fatigue. Photomed Laser Surg 28:653–658. https://doi.org/10.1089/pho.2009.2688

  28. 28.

    Borges LS, Cerqueira MS, dos Santos Rocha JA, Conrado LA, Machado M, Pereira R et al (2014) Light-emitting diode phototherapy improves muscle recovery after a damaging exercise. Lasers Med Sci. https://doi.org/10.1007/s10103-013-1486-z

  29. 29.

    De Marchi T, Leal ECP, Bortoli C, Tomazoni SS, Lopes-Martins RÁB, Salvador M (2012) Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress. Lasers Med Sci 27:231–236. https://doi.org/10.1007/s10103-011-0955-5

  30. 30.

    Denis R, O'Brien C, Delahunt E (2013) The effects of light emitting diode therapy following high intensity exercise. Phys Ther Sport 14(2):110–115. https://doi.org/10.1016/j.ptsp.2012.03.014

  31. 31.

    Felismino AS, Costa EC, Aoki MS, Ferraresi C, De Araújo Moura Lemos TM, De Brito Vieira WH (2014) Effect of low-level laser therapy (808 nm) on markers of muscle damage: a randomized double-blind placebo-controlled trial. Lasers Med Sci 29:933–938. https://doi.org/10.1007/s10103-013-1430-2

  32. 32.

    Ferraresi C, de Brito Oliveira T, De Oliveira Zafalon L, De Menezes Reiff RB, Baldissera V, de Andrade Perez SE et al (2011) Effects of low level laser therapy (808 nm) on physical strength training in humans. Lasers Med Sci 26:349–358. https://doi.org/10.1007/s10103-010-0855-0

  33. 33.

    Fritsch CG, Dornelles MP, Severo-Silveira L, Marques VB, Rosso IA, Baroni BM (2016) Effects of low-level laser therapy applied before or after plyometric exercise on muscle damage markers: randomized, double-blind, placebo-controlled trial. Lasers Med Sci 31(9):1935–1942. https://doi.org/10.1007/s10103-016-2072-y

  34. 34.

    Gorgey AS, Wadee AN, Sobhi NN (2008) The effect of low-level laser therapy on electrically induced muscle fatigue: a pilot study. Photomed Laser Surg 26:501–506. https://doi.org/10.1089/pho.2007.2161

  35. 35.

    Hemmings TJ, Kendall KL, Dobson JL (2017) Identifying dosage effect of light-emitting diode therapy on muscular fatigue in quadriceps. J Strength Cond Res 31(2):395–402. https://doi.org/10.1519/JSC.0000000000001523

  36. 36.

    Higashi RH, Toma RL, Tucci HT, Pedroni CR, Ferreira PD, Baldini G et al (2013) Effects of low-level laser therapy on biceps braquialis muscle fatigue in young women. Photomed Laser Surg 31:586–594. https://doi.org/10.1089/pho.2012.3388

  37. 37.

    Kelencz CA, Munoz IS, Amorim CF, Nicolau RA (2010) Effect of low-power gallium-aluminum-arsenium noncoherent light (640 nm) on muscle activity: a clinical study. Photomed Laser Surg 28(5):647–652. https://doi.org/10.1089/pho.2008.2467

  38. 38.

    Leal-Junior ECP, Lopes-Martins RA, Dalan F, Ferrari M, Sbabo FM, Generosi RA et al (2008) Effect of 655-nm low-level laser therapy on exercise-induced skeletal muscle fatigue in humans. Photomed Laser Surg. https://doi.org/10.1089/pho.2007.2160

  39. 39.

    Leal-Junior ECP, Lopes-Martins RA, Baroni BM, Marchi T, Rossi RP, Grosselli D et al (2009) Comparison between single-diode low-level laser therapy (LLLT) and LED multi-diode (cluster) therapy (LEDT) applications before high-intensity exercise. Photomed Laser Surg. https://doi.org/10.1089/pho.2008.2350

  40. 40.

    Leal-Junior ECP, Lopes-Martins RA, Rossi RP, Marchi T, Baroni BM, Godoi V et al (2009) Effect of cluster multi-diode light emitting diode therapy (LEDT) on exercise-induced skeletal muscle fatigue and skeletal muscle recovery in humans. Lasers Surg Med. https://doi.org/10.1002/lsm.20810

  41. 41.

    Leal-Junior ECP, Lopes-Martins RÁB, Baroni BM, De Marchi T, Taufer D, Manfro DS et al (2009) Effect of 830 nm low-level laser therapy applied before high-intensity exercises on skeletal muscle recovery in athletes. Lasers Med Sci 24:857–863. https://doi.org/10.1007/s10103-008-0633-4

  42. 42.

    Leal-Junior ECP, Lopes-Martins RABÁB, Vanin AA, Baroni BM, Grosselli D, De Marchi T et al (2009) Effect of 830 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in humans. Lasers Med Sci 24:425–431. https://doi.org/10.1007/s10103-008-0592-9

  43. 43.

    Leal-Junior ECP, Lopes-Martins RAB, Frigo L, De Marchi T, Rossi RP, de Godoi V et al (2010) Effects of low-level laser therapy (LLLT) in the development of exercise-induced skeletal muscle fatigue and changes in biochemical markers related to postexercise recovery. J Orthop Sports Phys Ther 40(8):524–532. https://doi.org/10.2519/jospt.2010.3294

  44. 44.

    Leal-Junior ECP, Godoi V, Mancalossi JL, Rossi RP, Marchi T, Parente M et al (2011) Comparison between cold water immersion therapy (CWIT) and light emitting diode therapy (LEDT) in short-term skeletal muscle recovery after high-intensity exercise in athletes--preliminary results. Lasers Med Sci. https://doi.org/10.1007/s10103-010-0866-x

  45. 45.

    Leal-Junior ECP, Baroni BM, Rossi RP, Godoi V, De Marchi T, Tomazoni SS et al (2011) Light emitting diode therapy (LEDT) applied pre-exercise inhibits lipid peroxidation in athletes after high-intensity exercise. A preliminary study. Rev Bras Med Esporte 17(1):8–12

  46. 46.

    Maciel TSS, Silva J, Jorge FS, Nicolau RA (2013) A influência do laser 830 nm no desempenho do salto de atletas de voleibol feminino. Braz J Biomed Eng 29(2):199–205

  47. 47.

    Malta ES, De Poli RA, Brisola GM, Milioni F, Miyagi WE, Machado FA et al (2016) Acute LED irradiation does not change the anaerobic capacity and time to exhaustion during a high-intensity running effort: a double-blind, crossover, and placebo-controlled study : effects of LED irradiation on anaerobic capacity and performance in running. Lasers Med Sci 31(7):1473–1480. https://doi.org/10.1007/s10103-016-2011-y

  48. 48.

    Pinto HD, Vanin AA, Miranda EF, Tomazoni SS, Johnson DS, Albuquerque-Pontes GM et al (2016) Photobiomodulation therapy improves performance and accelerates recovery of high-level rugby players in field test: a randomized, crossover, double-blind, placebo-controlled clinical study. J Strength Cond Res 30(12):3329–3338. https://doi.org/10.1519/JSC.0000000000001439

  49. 49.

    Reis FA, da Silva BA, Salvador Laraia EM, de Melo RM, Silva PH, Pinto Leal-Junior EC et al (2014) Effects of pre- or post-exercise low-level laser therapy (830 nm) on skeletal muscle fatigue and biochemical markers of recovery in humans: double-blind placebo-controlled trial. Photomed Laser Surg 32:106–112. https://doi.org/10.1089/pho.2013.3617

  50. 50.

    Rossato M, Dellagrana RA, Lanferdini FJ, Sakugawa RL, Lazzari CD, Baroni BM et al (2016) Effect of pre-exercise phototherapy applied with different cluster probe sizes on elbow flexor muscle fatigue. Lasers Med Sci 31(6):1237–1244. https://doi.org/10.1007/s10103-016-1973-0

  51. 51.

    Vanin AA, De Marchi T, Silva Tomazoni S, Tairova O, Leao Casalechi H, de Tarso Camillo de Carvalho P et al (2016) Pre-exercise infrared low-level laser therapy (810 nm) in skeletal muscle performance and postexercise recovery in humans, what is the optimal dose? A randomized, double-blind, placebo-controlled clinical trial. Photomed Laser Surg 34(10):473–482. https://doi.org/10.1089/pho.2015.3992

  52. 52.

    Vanin AA, Miranda EF, Machado CS, de Paiva PR, Albuquerque-Pontes GM, Casalechi HL et al (2016) What is the best moment to apply phototherapy when associated to a strength training program? A randomized, double-blinded, placebo-controlled trial: phototherapy in association to strength training. Lasers Med Sci 31(8):1555–1564. https://doi.org/10.1007/s10103-016-2015-7

  53. 53.

    Vieira WHB, Ferraresi C, Andrade Perez SE, Baldissera V, Parizotto NA (2012) Effects of low-level laser therapy (808 nm) on isokinetic muscle performance of young women submitted to endurance training: a randomized controlled clinical trial. Lasers Med Sci. https://doi.org/10.1007/s10103-011-0984-0

  54. 54.

    Vieira WHB, Bezerra RM, Queiroz RAS, Maciel NFB, Parizotto NA, Ferraresi C (2014) Use of low-level laser therapy (808 nm) to muscle fatigue resistance: a randomized double-blind crossover trial. Photomed Laser Surg 32(12):678–685. https://doi.org/10.1089/pho.2014.3812

  55. 55.

    Zagatto AM, de Paula Ramos S, Nakamura FY, de Lira FS, Lopes-Martins RÁB, de Paiva Carvalho RL (2016) Effects of low-level laser therapy on performance, inflammatory markers, and muscle damage in young water polo athletes: a double-blind, randomized, placebo-controlled study. Lasers Med Sci 31(3):511–521. https://doi.org/10.1007/s10103-016-1875-1

  56. 56.

    Ferraresi C, Dos Santos RV, Marques G, Zangrande M, Leonaldo R, Hamblin MR et al (2015) Light-emitting diode therapy (LEDT) before matches prevents increase in creatine kinase with a light dose response in volleyball players. Lasers Med Sci. https://doi.org/10.1007/s10103-015-1728-3

  57. 57.

    Bosquet L, Berryman N, Dupuy O, Mekary S, Arvisais D, Bherer L et al (2013) Effect of training cessation on muscular performance: a meta-analysis. Scand J Med Sci Sports 23(3):e140–e149. https://doi.org/10.1111/sms.12047

  58. 58.

    Bosquet L, Maquet D, Forthomme B, Nowak N, Lehance C, Croisier JL (2010) Effect of the lengthening of the protocol on the reliability of muscle fatigue indicators. Int J Sports Med 31(2):82–88. https://doi.org/10.1055/s-0029-1243168

  59. 59.

    Hegedus EJ, McDonough S, Bleakley C, Cook CE, Baxter GD (2015) Clinician-friendly lower extremity physical performance measures in athletes: a systematic review of measurement properties and correlation with injury, part 1. The tests for knee function including the hop tests. Br J Sports Med 49(10):642–648. https://doi.org/10.1136/bjsports-2014-094094

  60. 60.

    Castronovo AM, Conforto S, Schmid M, Bibbo D, D'Alessio T (2013) How to assess performance in cycling: the multivariate nature of influencing factors and related indicators. Front Physiol 4:1–10. https://doi.org/10.3389/fphys.2013.00116

  61. 61.

    Glaister M, Stone MH, Stewart AM, Hughes M, Moir GL (2004) The reliability and validity of fatigue measures during short-duration maximal-intensity intermittent cycling. J Strength Cond Res 18(3):459–462. https://doi.org/10.1519/1533-4287(2004)18<459:TRAVOF>2.0.CO;2

  62. 62.

    Vollestad NK (1997) Measurement of human muscle fatigue. J Neurosci Methods 74:219–227

  63. 63.

    Zhang J, Lockhart TE, Soangra R (2014) Classifying lower extremity muscle fatigue during walking using machine learning and inertial sensors. Ann Biomed Eng 42:600–612. https://doi.org/10.1007/s10439-013-0917-0

  64. 64.

    Hody S, Rogister B, Leprince P, Wang F, Croisier JL (2013) Muscle fatigue experienced during maximal eccentric exercise is predictive of the plasma creatine kinase (CK) response. Scand J Med Sci Sports 23(4):501–507. https://doi.org/10.1111/j.1600-0838.2011.01413.x

  65. 65.

    Johnston RD, Gabbett TJ, Seibold AJ, Jenkins DG (2014) Influence of physical contact on neuromuscular fatigue and markers of muscle damage following small-sided games. J Sci Med Sport 17(5):535–540. https://doi.org/10.1016/j.jsams.2013.07.018

  66. 66.

    Baroni BM, Rodrigues R, Freire BB, Franke RDA, Geremia JM, Vaz MA (2015) Effect of low-level laser therapy on muscle adaptation to knee extensor eccentric training. Eur J Appl Physiol 115:639–647. https://doi.org/10.1007/s00421-014-3055-y

  67. 67.

    Enoka RM, Duchateau J (2016) Translating fatigue to human performance. Med Sci Sports Exerc 48(11):2228–2238. https://doi.org/10.1249/MSS.0000000000000929

  68. 68.

    Lopes-Martins RA, Marcos RL, Leonardo PS, Prianti AC Jr, Muscara MN, Aimbire F et al (2006) Effect of low-level laser (Ga-Al-As 655 nm) on skeletal muscle fatigue induced by electrical stimulation in rats. J Appl Physiol (1985) 101(1):283–288. https://doi.org/10.1152/japplphysiol.01318.2005

  69. 69.

    Li T, Yu T, Hawkins BS, Dickersin K (2015) Design, analysis, and reporting of crossover trials for inclusion in a meta-analysis. PLoS One 10(8):e0133023. https://doi.org/10.1371/journal.pone.0133023

  70. 70.

    Elbourne DR, Altman DG, Higgins JP, Curtin F, Worthington HV, Vail A (2002) Meta-analyses involving cross-over trials: methodological issues. Int J Epidemiol 31(1):140–149

  71. 71.

    Mills EJ, Chan AW, Wu P, Vail A, Guyatt GH, Altman DG (2009) Design, analysis, and presentation of crossover trials. Trials 10:27. https://doi.org/10.1186/1745-6215-10-27

  72. 72.

    Nampo FK, Weiss C, Porzsolt F (2016) Comments on “light-emitting diode therapy (ledt) before matches prevents increase in creatine kinase with a light dose response in volleyball players”. Lasers Med Sci 31(6):1273–1274. https://doi.org/10.1007/s10103-016-1940-9

  73. 73.

    Stewart L, Moher D, Shekelle P (2012) Why prospective registration of systematic reviews makes sense. Syst Rev 1:7. https://doi.org/10.1186/2046-4053-1-7

  74. 74.

    Lopes-Martins RA, Mafra FP, De Nucci G (2016) Laser therapy and muscle fatigue: a promising research area. Photomed Laser Surg 34(7):273–275. https://doi.org/10.1089/pho.2016.4130

  75. 75.

    Moher D, Hopewell S, Schulz KF, Montori V, Gotzsche PC, Devereaux PJ et al (2010) CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol 63(8):e1–37. https://doi.org/10.1016/j.jclinepi.2010.03.004

  76. 76.

    Costa LO, Maher CG, Lopes AD, de Noronha MA, Costa LC (2011) Transparent reporting of studies relevant to physical therapy practice. Rev Bras Fisioter 15(4):267–271

  77. 77.

    Yamato T, Maher C, Saragiotto B, Moseley A, Hoffmann T, Elkins M et al (2016) The TIDieR checklist will benefit the physical therapy profession. J Orthop Sports Phys Ther 46(6):402–404. https://doi.org/10.2519/jospt.2016.0108

  78. 78.

    Jenkins PA, Carroll JD (2011) How to report low-level laser therapy (LLLT)/photomedicine dose and beam parameters in clinical and laboratory studies. Photomed Laser Surg 29(12):785–787. https://doi.org/10.1089/pho.2011.9895

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Correspondence to Ernesto Cesar Pinto Leal-Junior.

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Conflict of interests

Professor Ernesto Cesar Pinto Leal-Junior receives research support from Multi Radiance Medical (Solon, OH, USA), a laser device manufacturer. AAV, EV, SDB, and LPC declare that they have no conflicts of interest.

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Vanin, A.A., Verhagen, E., Barboza, S.D. et al. Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis. Lasers Med Sci 33, 181–214 (2018). https://doi.org/10.1007/s10103-017-2368-6

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Keywords

  • Phototherapy
  • Low-level light therapy
  • Light emitting diode
  • Performance
  • Fatigue
  • Exercise