Does addition of low-level laser therapy (LLLT) in conservative care of knee arthritis successfully postpone the need for joint replacement?
- 804 Downloads
The current study evaluates whether the addition of low-level laser therapy into standard conventional physical therapy in elderly with bilateral symptomatic tri-compartmental knee arthritis can successfully postpone the need for joint replacement surgery. A prospective randomized cohort study of 100 consecutive unselected elderly patients with bilateral symptomatic knee arthritis with each knee randomized to receive either treatment protocol A consisting of conventional physical therapy or protocol B which is the same as protocol A with added low-level laser therapy. The mean follow-up was 6 years. Treatment failure was defined as breakthrough pain which necessitated joint replacement surgery. After a follow-up of 6 years, patients clearly benefited from treatment with protocol B as only one knee needed joint replacement surgery, while nine patients treated with protocol A needed surgery (p < 0.05). We conclude low-level laser therapy should be incorporated into standard conservative treatment protocol for symptomatic knee arthritis.
KeywordsKnee pain Osteoarthritis Outcome Laser therapy
Compliance with ethical standards
All elderly who entered the study were made known to the details of the study, signed consent, and agreed to come for periodic follow-up. All patients signed informed consent that they will be treated by low-level laser therapy machines approved by FDA, and that either Protocol A or B will be assigned at random.
No grants or supports from any company or institution were received for this study.
- 2.Hashmi JT, Huang YY, Osmani BZ, Sharma SK, Naeser MA, Hamblin MR (2010) Role of low-level laser therapy in neuro-rehabilitation. Am Acad Phys Med Rehab 2(12 Suppl 2):S292–S305Google Scholar
- 4.Lam TS, Abergel RP, Meeker CA, Castel JC, Dwyer RM, Uitto J (1986) Laser stimulation of collagen synthesis in human skin fibroblasts cultures. Lasers Life Sci 1:61–77Google Scholar
- 5.Brousseau L, Welch V, Wells G, Tugwell P, de Bie R, Gam A et al (2000) Low level laser therapy for osteoarthritis and rheumatoid arthritis: a meta-analysis. J Rheumatol 27(8):1961–1969Google Scholar
- 8.Welch V, Brosseau L, Peterson J, Shea B, Tugwell P, Wells G (2001) Therapeutic ultrasound for osteoarthritis of the knee. Cochrane Database Syst Rev 2001(3):CD003132Google Scholar
- 10.Osiri M, Welch V, Brosseau L, Shea B, Mcgowan J, Tugwell P et al (2007) Transcutaneous electrical nerve stimulation for knee osteoarthritis (Review). Cochrane Libr (4)Google Scholar
- 11.Rayegani SM, Bahrami MH, Elyaspour D, Saeidi M, Sanjari H (2012) Therapeutic effects of low-level laser therapy (LLLT) in knee osteoarthritis, compared to therapeutic ultrasound. J Lasers Med Sci 3(2)Google Scholar
- 12.Ip David (2007) Orthopedic rehabilitation, assessment and enablement. Springer-Verlag Heidelberg, Germany. Chapter 2Google Scholar
- 13.Baker KG, Robertson VJ, Duck FA (2001) A review of therapeutic ultrasound: biophysical effects. Phys Ther 811351–1358.1358Google Scholar