Lasers in Medical Science

, Volume 29, Issue 2, pp 765–771 | Cite as

Endovenous laser ablation of the great saphenous vein versus high ligation: long-term results

  • Mohammad MozafarEmail author
  • Khashayar Atqiaee
  • Hamidreza Haghighatkhah
  • Morteza Sanei Taheri
  • Ali Tabatabaey
  • Saran Lotfollahzadeh
Original Article


Endovenous laser therapy (EVLT) for greater saphenous vein (GSV) insufficiency is a relatively new method of treatment only recently made available in Iran. This is the first long-term randomized trial comparing EVLT with high ligation of saphenous vein (HLS) in the Iranian population. Sixty-five patients met the inclusion criteria and were divided into homogenous treatment groups of EVLT (n = 30) or HLS (n = 35). Clinical severity, etiology, anatomy, pathophysiology (CEAP) classification and Aberdeen Varicose Vein Symptom Severity Scores (AVSS) were used to determine disease severity and symptoms before and after the procedure in both groups. Outcome was measured by the rate of recurrence as shown in Doppler ultrasonography evaluation. Follow-up was conducted 1 week and 3, 6, 12, and 18 months after the intervention. The occlusion rate of GSV was similar in both groups (93.6 % for EVLT, 88.3 for HLS) at 18 months of follow-up. The median CEAP score showed a dramatic decrease in both groups after 1 week which was sustained for the rest of the study. The Aberdeen Varicose Vein Symptom Severity score was significantly lower in the EVLT group at 12 and 18 months of follow-up. There was no significant difference in patient satisfaction in both groups. Our findings show that EVLT may offer a better long-term relief of symptoms. This, alongside its better cosmetic outcome, and less invasive anesthesia requirements may make it the favorable choice for treatment of GSV insufficiency.


Laser therapy Saphenous veins Venous insufficiencies 



The authors would like to thank Dr Tina Hedayat, Dr Azadeh Sadraie, and Zahra Razzaghi for their great contribution to the gathering and analysis of the data presented in this study.


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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Mohammad Mozafar
    • 1
    Email author
  • Khashayar Atqiaee
    • 2
  • Hamidreza Haghighatkhah
    • 2
  • Morteza Sanei Taheri
    • 2
  • Ali Tabatabaey
    • 3
  • Saran Lotfollahzadeh
    • 2
  1. 1.Shohada-e Tajrish Medical CenterTehranIran
  2. 2.Laser Application in Medical Sciences Research CenterShahid Beheshti University of Medical SciencesTehranIran
  3. 3.Department of Emergency MedicineShahid Beheshti University of Medical SciencesTehranIran

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