Lasers in Medical Science

, Volume 23, Issue 4, pp 349–353 | Cite as

The effects of laser irradiation on Trichophyton rubrum growth

  • Emre VuralEmail author
  • Harry L. Winfield
  • Alexander W. Shingleton
  • Thomas D. Horn
  • Gal Shafirstein
Original Article


The effects of various laser wavelengths and fluences on the fungal isolate, Trichophyton rubrum, were examined in vitro. Standard-size isolates of T. rubrum were irradiated by using various laser systems. Colony areas were compared for growth inhibition on days 1, 3, and 6 after laser irradiation. Statistically significant growth inhibition of T. rubrum was detected in colonies treated with the 1,064-nm Q-switched Nd:YAG laser at 4 and 8 J/cm2 and 532-nm Q-switched Nd:YAG laser at 8 J/cm2. Q-switched Nd:YAG laser at 532- and 1,064-nm wavelengths produced significant inhibitory effect upon the fungal isolate T. rubrum in this in vitro study. However, more in vitro and in vivo studies are necessary to investigate if lasers would have a potential use in the treatment of fungal infections of skin and its adnexa.


Laser Dermatophyte Fungus 


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Copyright information

© Springer-Verlag London Limited 2007

Authors and Affiliations

  • Emre Vural
    • 1
    • 2
    Email author
  • Harry L. Winfield
    • 3
  • Alexander W. Shingleton
    • 4
  • Thomas D. Horn
    • 5
  • Gal Shafirstein
    • 1
  1. 1.Department of Otolaryngology-Head and Neck SurgeryUniversity of Arkansas for Medical SciencesLittle RockUSA
  2. 2.Division of Otolaryngology-Head and Neck SurgeryJohn McClellan VA HospitalLittle RockUSA
  3. 3.Department of PathologyUniversity of Arkansas for Medical SciencesLittle RockUSA
  4. 4.Ecology, Evolutionary Biology & Behavior Program, Department of ZoologyMichigan State UniversityEast LansingUSA
  5. 5.Department of DermatologyUniversity of Arkansas for Medical SciencesLittle RockUSA

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