Lasers in Medical Science

, Volume 21, Issue 3, pp 126–133 | Cite as

New dimensions in Hirsutism

  • V. A. Randall
  • S. Lanigan
  • I. Hamzavi
  • L. Chamberlain JamesEmail author
Review Article


The following is a review of a satellite symposium held at the British Medical Laser Association Meeting, in November 2005. Prof. V.A. Randall gave a comprehensive overview of hormones and hair growth, followed by an in-depth discussion of hirsutism, the therapeutic options, treatment and trends, by Dr. S. Lanigan. Dr. I. Hamzavi concluded the symposium with a presentation of the latest work on eflornithine in combination with laser hair removal. Data were reproduced with the speakers’ permission.


Hirsutism Hair Hormones Lasers Eflornithine 



The authors gratefully acknowledge the assistance of Dr. Lisa Chamberlain James in the preparation of this manuscript.


  1. 1.
    Randall VA (2004) The paradoxical effects of androgens on human hair growth. In: Nieschlag E, Behre HM (eds) Testosterone: action, deficiency, substitution, 3rd edn. Cambridge University Press, Cambridge, pp 207–231Google Scholar
  2. 2.
    Randall VA, Ebling FJG (1991) Seasonal changes in human hair growth. Br J Dermatol 124:146–151PubMedCrossRefGoogle Scholar
  3. 3.
    Jahoda CAB, Reynolds AJ (1996) Dermal–epidermal interactions. Adult follicle-derived cell populations and hair growth. Dermatol Clin 14:573–583PubMedCrossRefGoogle Scholar
  4. 4.
    Hamada K, Randall VA (2006) Inhibitory paracrine factors produced by the mesenchyme-derived hair follicle dermal papilla may be a key to male pattern baldness. Br J Dermatol (in press)Google Scholar
  5. 5.
    Bouzari N, Tabatabai H, Abbasi Z et al (2004) Laser hair removal: comparison of long-pulsed Nd:YAG, long-pulsed alexandrite, and long-pulsed diode lasers. Dermatol Surg 30:498PubMedCrossRefGoogle Scholar
  6. 6.
    Marayiannis KB, Vlachos SP, Savva MP et al (2003) Efficacy of long- and short pulse alexandrite lasers compared with an intense pulsed light source for epilation: a study on 532 sites in 389 patients. J Cosmet Laser Ther 5:140–145PubMedCrossRefGoogle Scholar
  7. 7.
    Ross EV, Cooke LM, Overstreet KA et al (2002) Treatment of pseudofolliculitis barbae in very dark skin with a long pulse Nd:YAG laser. J Natl Med Assoc 94:888–893PubMedGoogle Scholar
  8. 8.
    Sadick NS, Shaoul J (2004) Hair removal using a combination of conducted radiofrequency and optical energies—an 18-month follow-up. J Cosmet Laser Ther 6:21–26PubMedCrossRefGoogle Scholar
  9. 9.
    Sadick NS, Laughlin SA (2004) Effective epilation of white and blond hair using combined radiofrequency and optical energy. J Cosmet Laser Ther 6:27–31PubMedCrossRefGoogle Scholar
  10. 10.
    Lanigan SW (2003) Incidence of side effects after laser hair removal. J Am Acad Dermatol 49(5):882–886PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2006

Authors and Affiliations

  • V. A. Randall
    • 1
  • S. Lanigan
    • 2
  • I. Hamzavi
    • 3
    • 4
    • 6
  • L. Chamberlain James
    • 5
    Email author
  1. 1.Department of Biomedical SciencesUniversity of BradfordBradfordUK
  2. 2.Birmingham Skin CentreCity Hospital NHS TrustBirminghamUK
  3. 3.Henry Ford HospitalDetroitUSA
  4. 4.Wayne State UniversityDetroitUSA
  5. 5.Mill House, Whitetome Mill, HilgayNorfolkUK
  6. 6.Port HuronUSA

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