HIV-1 Plasma Viremia not Increased in Patients Receiving Highly Active Antiretroviral Therapy After Influenza Vaccination

  • J. Macías
  • J. A. Pineda
  • M. Leal
  • M. A. Abad
  • J. Delgado
  • R. Rosa
  • A. Rubio
  • A. Sánchez-Quijano
  • E. Lissen
Note

DOI: 10.1007/s100960000421

Cite this article as:
Macías, J., Pineda, J., Leal, M. et al. EJCMID (2001) 20: 46. doi:10.1007/s100960000421

Abstract

 The effect of vaccinating patients with sustained undetectable HIV-1 viremia (VL) achieved with highly active antiretroviral therapy was prospectively investigated. During the 1998 influenza immunization period, 39 HIV-1-infected patients who showed a VL<20 copies/ml for at least 6 months before the study entry date were vaccinated for influenza. Twenty-two vaccinees were immunized at entry. Seventeen controls were followed for 4 weeks after entry, crossing over then to the vaccination group. The proportion of patients with undetectable VL was not significantly different between the vaccination and control groups 2 and 4 weeks after entry. Therefore, influenza immunization of patients with undetectable viremia achieved with highly active antiretroviral therapy does not seem to affect VL.

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • J. Macías
    • 1
  • J. A. Pineda
    • 1
  • M. Leal
    • 2
  • M. A. Abad
    • 3
  • J. Delgado
    • 2
  • R. Rosa
    • 2
  • A. Rubio
    • 3
  • A. Sánchez-Quijano
    • 2
  • E. Lissen
    • 2
  1. 1.Viral Hepatitis and AIDS Study Group, Servicio de Medicina Interna, Hospital Universitario Virgen de Valme, Carretera de Cádiz s/n, 41014 Seville, Spain e-mail: jmacias@cica.es Tel.: +34-5-4252525 Fax: +34-5-4248249ES
  2. 2.Viral Hepatitis and AIDS Study Group, Servicio de Medicina Interna, Hospital Universitario Virgen del Rocío, Avda. Manuel Siurot s/n, 41013 Seville, SpainES
  3. 3.Viral Hepatitis and AIDS Study Group, Servicio de Bioquímica, Hospital Universitario Virgen del Rocío, Avenida Manuel Siurot s/n, 41013 Seville, SpainES

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