Social determinants associated with Giardia duodenalis infection in southern Côte d’Ivoire

  • F. Berrilli
  • D. Di Cave
  • R. N’Guessan
  • Y. Kaboré
  • A. Giangaspero
  • R. P. Sorge
  • R. D’Alfonso
Article

Abstract

The purpose of this investigation was to analyze the association between different social determinants of health at the local scale and Giardia duodenalis infection in diverse settlements in southern Côte d’Ivoire. Stool samples from 306 individuals aged 1–16 years were collected from six rural villages and a small town. Five variables were categorized to classify the increasing risk levels of acquiring intestinal parasites. Giardia prevalences (%) and odds ratios (ORs) were evaluated. Correlation and regression analyses were conducted to determine the correlation coefficients and to propose predictive models based on social determinants to forecast the risk of giardiasis. The overall observed prevalence of Giardia was 21.6 %. When the analysis was conducted at the local level, the percentage of infected people varied from a minimum of 12.7 up to 36.4 %. A significant association (p < 0.001) was found between the selected social determinants and G. duodenalis prevalence in the different localities. Correlation and regression analyses allowed us to describe two predictive models to estimate the OR of Giardia transmission. This study helps to clarify the possible impact of different social determinants of health on the risk of giardiasis at the local scale. Both predictive models could be suitable in order to assess the likelihood of the transmission of intestinal parasitic infection in developing countries.

References

  1. 1.
    Savioli L, Smith H, Thompson A (2006) Giardia and Cryptosporidium join the ‘Neglected Diseases Initiative’. Trends Parasitol 22:203–208PubMedCrossRefGoogle Scholar
  2. 2.
    Ayalew D, Boelee E, Endeshaw T, Petros B (2008) Cryptosporidium and Giardia infection and drinking water sources among children in Lege Dini, Ethiopia. Trop Med Int Health 13:472–475PubMedCrossRefGoogle Scholar
  3. 3.
    Nyarango RM, Aloo PA, Kabiru EW, Nyanchongi BO (2008) The risk of pathogenic intestinal parasite infections in Kisii Municipality, Kenya. BMC Public Health 8:237PubMedCrossRefPubMedCentralGoogle Scholar
  4. 4.
    Gamboa MI, Navone GT, Orden AB, Torres MF, Castro LE, Oyhenart EE (2011) Socio-environmental conditions, intestinal parasitic infections and nutritional status in children from a suburban neighborhood of La Plata, Argentina. Acta Trop 118:184–189PubMedCrossRefGoogle Scholar
  5. 5.
    Karan A, Chapman GB, Galvani A (2012) The influence of poverty and culture on the transmission of parasitic infections in rural nicaraguan villages. J Parasitol Res 2012:478292. doi:10.1155/2012/478292 PubMedCrossRefPubMedCentralGoogle Scholar
  6. 6.
    Harhay MO, Horton J, Olliaro PL (2010) Epidemiology and control of human gastrointestinal parasites in children. Expert Rev Anti Infect Ther 8:219–234PubMedCrossRefPubMedCentralGoogle Scholar
  7. 7.
    Adou-Bryn D, Kouassi M, Brou J, Ouhon J, Assoumou A (2001) Widespread prevalence of orally transmitted intestinal parasitoses in children in Toumodi (Côte d’Ivoire). Méd Afr Noire 48:394–398Google Scholar
  8. 8.
    Raso G, Utzinger J, Silué KD, Ouattara M, Yapi A, Toty A, Matthys B, Vounatsou P, Tanner M, N’Goran EK (2005) Disparities in parasitic infections, perceived ill health and access to health care among poorer and less poor schoolchildren of rural Côte d’Ivoire. Trop Med Int Health 10:42–57PubMedCrossRefGoogle Scholar
  9. 9.
    Niangué-Beugré NN, Couitchéré L, Oulai SM, Cissé L, Enoh J (2006) Epidemiological, clinical, etiological aspects of acute diarrheas among children aged from 1 month to 5 years in the pediatric ward of UCH of Treichville. Arch Pediatr 13:395–396PubMedCrossRefGoogle Scholar
  10. 10.
    Ouattara M, N’Guéssan NA, Yapi A, N’Goran EK (2010) Prevalence and spatial distribution of Entamoeba histolytica/dispar and Giardia lamblia among schoolchildren in Agboville area (Côte d’Ivoire). PLoS Negl Trop Dis 4:e574. doi:10.1371/journal.pntd.0000574 PubMedCrossRefPubMedCentralGoogle Scholar
  11. 11.
    Schmidlin T, Hürlimann E, Silué KD, Yapi RB, Houngbedji C, Kouadio BA, Acka-Douabélé CA, Kouassi D, Ouattara M, Zouzou F, Bonfoh B, N’Goran EK, Utzinger J, Raso G (2013) Effects of hygiene and defecation behavior on helminths and intestinal protozoa infections in Taabo, Côte d’Ivoire. PLoS One 8:e65722. doi:10.1371/journal.pone.0065722 PubMedCrossRefPubMedCentralGoogle Scholar
  12. 12.
    Utzinger J, Botero-Kleiven S, Castelli F, Chiodini PL, Edwards H, Köhler N, Gulletta M, Lebbad M, Manser M, Matthys B, N’Goran EK, Tannich E, Vounatsou P, Marti H (2010) Microscopic diagnosis of sodium acetate-acetic acid-formalin-fixed stool samples for helminths and intestinal protozoa: a comparison among European reference laboratories. Clin Microbiol Infect 16:267–273PubMedCrossRefGoogle Scholar
  13. 13.
    Raso G, Luginbühl A, Adjoua CA, Tian-Bi NT, Silué KD, Matthys B, Vounatsou P, Wang Y, Dumas ME, Holmes E, Singer BH, Tanner M, N’goran EK, Utzinger J (2004) Multiple parasite infections and their relationship to self-reported morbidity in a community of rural Côte d’Ivoire. Int J Epidemiol 33:1092–1102PubMedCrossRefGoogle Scholar
  14. 14.
    Leach CT, Koo FC, Kuhls TL, Hilsenbeck SG, Jenson HB (2000) Prevalence of Cryptosporidium parvum infection in children along the Texas–Mexico border and associated risk factors. Am J Trop Med Hyg 62:656–661PubMedGoogle Scholar
  15. 15.
    Iqbal J, Hira PR, Al-Ali F, Philip R (2001) Cryptosporidiosis in Kuwaiti children: seasonality and endemicity. Clin Microbiol Infect 7:261–266PubMedCrossRefGoogle Scholar
  16. 16.
    Nichols G, Lane C, Asgari N, Verlander NQ, Charlett A (2009) Rainfall and outbreaks of drinking water related disease and in England and Wales. J Water Health 7:1–8PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • F. Berrilli
    • 1
  • D. Di Cave
    • 1
  • R. N’Guessan
    • 2
  • Y. Kaboré
    • 2
  • A. Giangaspero
    • 3
  • R. P. Sorge
    • 4
  • R. D’Alfonso
    • 2
    • 5
  1. 1.Department of Experimental Medicine and SurgeryUniversity of Rome Tor VergataRomeItaly
  2. 2.Centre Don Orione Pour Handicapés PhysiquesBonouaCôte d’Ivoire
  3. 3.Dipartimento di Scienze Agrarie, Degli Alimenti e dell’AmbienteUniversity of FoggiaFoggiaItaly
  4. 4.Laboratory of BiometryUniversity of Rome Tor VergataRomeItaly
  5. 5.Department of Systems MedicineUniversity of Rome Tor VergataRomeItaly

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