Diplorickettsia massiliensis as a human pathogen

  • G. Subramanian
  • O. Mediannikov
  • E. Angelakis
  • C. Socolovschi
  • G. Kaplanski
  • L. Martzolff
  • D. Raoult
Article

Abstract

Diplorickettsia massiliensis has been recently isolated from Ixodes ricinus ticks. We screened 13,872 serum samples from patients in France with suspected tick-borne diseases and found three cases that had serological evidence of D. massiliensis infection; for one of these three cases, we obtained molecular evidence of an infection as well.

References

  1. 1.
    Mediannikov O, Sekeyová Z, Birg ML, Raoult D (2010) A novel obligate intracellular gamma-proteobacterium associated with ixodid ticks, Diplorickettsia massiliensis, Gen. Nov., Sp. Nov. PLoS One 5:e11478PubMedCrossRefGoogle Scholar
  2. 2.
    Parola P, Raoult D (2001) Ticks and tickborne bacterial diseases in humans: an emerging infectious threat. Clin Infect Dis 32:897–928PubMedCrossRefGoogle Scholar
  3. 3.
    Jado I, Oteo JA, Aldámiz M, Gil H, Escudero R, Ibarra V, Portu J, Portillo A, Lezaun MJ, García-Amil C, Rodríguez-Moreno I, Anda P (2007) Rickettsia monacensis and human disease, Spain. Emerg Infect Dis 13(9):1405–1407PubMedGoogle Scholar
  4. 4.
    Raoult D, Dasch GA (1989) Line blot and western blot immunoassays for diagnosis of Mediterranean spotted fever. J Clin Microbiol 27:2073–2079PubMedGoogle Scholar
  5. 5.
    James AM, Liveris D, Wormser GP, Schwartz I, Montecalvo MA, Johnson BJ (2001) Borrelia lonestari infection after a bite by an Amblyomma americanum tick. J Infect Dis 183:1810–1814PubMedCrossRefGoogle Scholar
  6. 6.
    Buller RS, Arens M, Hmiel SP, Paddock CD, Sumner JW, Rikhisa Y, Unver A, Gaudreault-Keener M, Manian FA, Liddell AM, Schmulewitz N, Storch GA (1999) Ehrlichia ewingii, a newly recognized agent of human ehrlichiosis. N Engl J Med 341:148–155PubMedCrossRefGoogle Scholar
  7. 7.
    Maeda K, Markowitz N, Hawley RC, Ristic M, Cox D, McDade JE (1987) Human infection with Ehrlichia canis, a leukocytic rickettsia. N Engl J Med 316:853–856PubMedCrossRefGoogle Scholar
  8. 8.
    Bakken JS, Krueth J, Wilson-Nordskog C, Tilden RL, Asanovich K, Dumler JS (1996) Clinical and laboratory characteristics of human granulocytic ehrlichiosis. JAMA 275:199–205PubMedCrossRefGoogle Scholar
  9. 9.
    Carpenter CF, Gandhi TK, Kong LK, Corey GR, Chen SM, Walker DH, Dumler JS, Breitschwerdt E, Hegarty B, Sexton DJ (1999) The incidence of ehrlichial and rickettsial infection in patients with unexplained fever and recent history of tick bite in central North Carolina. J Infect Dis 180:900–903PubMedCrossRefGoogle Scholar
  10. 10.
    Belongia EA, Reed KD, Mitchell PD, Mueller-Rizner N, Vandermause M, Finkel MF, Kazmierczak JJ (2001) Tickborne infections as a cause of nonspecific febrile illness in Wisconsin. Clin Infect Dis 32:1434–1439PubMedCrossRefGoogle Scholar
  11. 11.
    Lotric-Furlan S, Petrovec M, Avsic-Zupanc T, Nicholson WL, Sumner JW, Childs JE, Strle F (2001) Prospective assessment of the etiology of acute febrile illness after a tick bite in Slovenia. Clin Infect Dis 33:503–510PubMedCrossRefGoogle Scholar
  12. 12.
    Parola P, Rovery C, Rolain JM, Brouqui P, Davoust B, Raoult D (2009) Rickettsia slovaca and R. raoultii in tick-borne Rickettsioses. Emerg Infect Dis 15:1105–1108PubMedCrossRefGoogle Scholar
  13. 13.
    Fournier PE, Grunnenberger F, Jaulhac B, Gastinger G, Raoult D (2000) Evidence of Rickettsia helvetica infection in humans, eastern France. Emerg Infect Dis 6:389–392PubMedCrossRefGoogle Scholar
  14. 14.
    Raoult D, Brouqui P, Roux V (1996) A new spotted-fever-group rickettsiosis. Lancet 348:412PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • G. Subramanian
    • 1
  • O. Mediannikov
    • 1
  • E. Angelakis
    • 1
  • C. Socolovschi
    • 1
  • G. Kaplanski
    • 2
  • L. Martzolff
    • 3
  • D. Raoult
    • 1
  1. 1.Unité des Rickettsies, Faculté de MédecineUniversité de la Méditerranée, URMITE, UMR CNRS 6236—IRD198Marseille Cedex 05France
  2. 2.Service de Médicine InterneCHU ConceptionMarseilleFrance
  3. 3.Service de Médecine Interne et EnodocrinologieHôpital Emile MullerMulhouse CedexFrance

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