Prevalence of faecal ESBL carriage in the community and in a hospital setting in a county of Southern Sweden
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The aim of this study was to investigate the prevalence of extended-spectrum beta-lactamase (ESBL)-producing bacteria in patients at various hospital wards and in a group of relatively healthy volunteers, in order to obtain greater knowledge on how common these bacterial strains are in hospital settings and in the general community. Participants (n = 427) were enrolled at a University Hospital and at Primary Health Care Units (PHCUs) in Sweden in 2008 and 2010. The participants provided rectal swabs, which were tested for the occurrence of ESBL-producing bacteria. Positive samples were analysed with polymerase chain reaction (PCR) methods for bacterial strain typing and ESBL phylogroups. In 2008, the prevalence was 2.1% (2/96) in PHCU subjects and 1.8% (2/113) in hospital patients. In 2010, the prevalence was 3.0% (3/100) in PHCU subjects and 6.8% (8/118) in hospital patients. The dominating phylogroups were CTX-M-1 and CTX-M-9. All ESBL-positive isolates were Escherichia coli. We found a higher prevalence of ESBL faecal carriage than expected, both in the hospital setting and in the PHCU group.
KeywordsAmpC Primary Health Care Unit TaqMan Polymerase Chain Reaction Faecal Carriage Bacterial Strain Typing
We wish to acknowledge the assistance of the following individuals: Bodil Ekblad, Lisbeth Elfström and Agneta Hamberg, laboratory technicians, Medical Microbiology, Department of Laboratory Medicine, Malmö, Lund University, Sweden; Charlotta Hagstam, Mikael Karlsson and Håkan Sjöholm, PHCUs Anderslöv, Sjöbo and Eden Malmö, Sweden; Karin Tegmark Wisell, Unit for Antibiotics and Infection Control, Swedish Institute for Communicable Disease Control, Solna, Sweden.
Declaration of interest
None to declare.
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