Bacillus cereus bacteremia outbreak due to contaminated hospital linens
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We describe an outbreak of Bacillus cereus bacteremia that occurred at Jichi Medical University Hospital in 2006. This study aimed to identify the source of this outbreak and to implement appropriate control measures. We reviewed the charts of patients with blood cultures positive for B. cereus, and investigated B. cereus contamination within the hospital environment. Genetic relationships among B. cereus isolates were analyzed. Eleven patients developed B. cereus bacteremia between January and August 2006. The hospital linens and the washing machine were highly contaminated with B. cereus, which was also isolated from the intravenous fluid. All of the contaminated linens were autoclaved, the washing machine was cleaned with a detergent, and hand hygiene was promoted among the hospital staff. The number of patients per month that developed new B. cereus bacteremia rapidly decreased after implementing these measures. The source of this outbreak was B. cereus contamination of hospital linens, and B. cereus was transmitted from the linens to patients via catheter infection. Our findings demonstrated that bacterial contamination of hospital linens can cause nosocomial bacteremia. Thus, blood cultures that are positive for B. cereus should not be regarded as false positives in the clinical setting.
KeywordsIntravenous Fluid Hand Hygiene Bacillus Species Sterile Physiological Saline Blood Culture Result
This work was supported in part by a Grant-in-Aid for Scientific Research (grant 19590519) from the Japan Society for the Promotion of Science.
- 1.Logan NA (2005) Bacillus anthracis, Bacillus cereus, and other aerobic endospore-forming bacteria. In: Borriello SP, Murray PR, Funke G (eds) Topley & Wilson’s Microbiology & Microbial Infections, Bacteriology, vol 2, 10th edn. American Society for Microbiology, Washington, DC, pp 922–952Google Scholar
- 7.Van Der Zwet WC, Parlevliet GA, Savelkoul PH, Stoof J, Kaiser AM, Van Furth AM, Vandenbroucke-Grauls CM (2000) Outbreak of Bacillus cereus infections in a neonatal intensive care unit traced to balloons used in manual ventilation. J Clin Microbiol 38:4131–4136Google Scholar
- 8.Briley RT, Teel JH, Forler JP (2001) Nontypical Bacillus cereus outbreak in a child care center. J Environ Health 63(9–11):21Google Scholar
- 9.Kalpoe JS, Hogenbirk K, van Maarseveen NM, Gesink-Van der Veer BJ, Kraakman ME, Maarleveld JJ, van der Reyden TJ, Dijkshoorn L, Bernards AT (2008) Dissemination of Bacillus cereus in a paediatric intensive care unit traced to insufficient disinfection of reusable ventilator air-flow sensors. J Hosp Infect 68:341–347CrossRefPubMedGoogle Scholar
- 32.Boyce JM, Pittet D, Healthcare Infection Control Practices Advisory Committee, HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force (2002) Guideline for hand hygiene in health-care settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. MMWR Recomm Rep 51:1–45PubMedGoogle Scholar