Cryptosporidiosis: environmental, therapeutic, and preventive challenges

Review

Abstract

Cryptosporidium spp. are responsible for endemic and epidemic disease worldwide. Clinical manifestations may include acute, persistent, or chronic diarrhea, biliary, and pulmonary disease. Disease severity ranges from asymptomatic or mild to severe, intractable diarrhea with wasting depending on immune status, nutrition, and age. Transmission is fecal–oral with both human and animal reservoirs. Disease is often self limited in healthy individuals, but therapy remains a challenge in the immune-compromised. Prevention currently depends on appropriate hygiene and proper water management and treatment.

Notes

Acknowledgements

SCA receives research support through the NIH grant 2 T32 AI007329-16.

Conflict of interest

None.

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  1. 1.Division of Geographic Medicine and Infectious DiseasesTufts Medical CenterBostonUSA
  2. 2.Tufts UniversityBostonUSA
  3. 3.Tufts Medical CenterBostonUSA

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