Isolation of Corynebacterium ureicelerivorans from normally sterile sites in humans

  • M. I. Fernández-Natal
  • J. A. Sáez-Nieto
  • S. Valdezate
  • R. H. Rodríguez-Pollán
  • S. Lapeña
  • F. Cachón
  • F. Soriano
Concise Article


Fifteen Corynebacterium ureicelerivorans isolates were recovered in pure culture from six patients during a five-year period. Five patients had bacteremia and the other was an infection of ascitic fluid. The API Coryne™ numerical profile obtained corresponds to the profile for C. bovis, while Biolog™ GP2 identified four out of the six isolates as C. jeikeium. The organisms were molecular identified by 16S rDNA and rpoB. The present report also includes information on new phenotypic tests and, for the first time, antimicrobial susceptibility data of C. ureicelerivorans and their rpoB sequences. All macrolide-resistant isolates presented a constitutive MLS phenotype. This organism must be differentiated from other slow-growing, lipophilic, and urea-splitting corynebacteria.


Clarithromycin Diverticulitis Linezolid Blood Agar Ascitic Fluid 
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This study has been supported by the Fondo de Investigaciones Sanitarias, Instituto de Salud Carlos III, Madrid, Spain, Research Project 03/0534.

Potential conflicts of interest

All authors: no conflicts.


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • M. I. Fernández-Natal
    • 1
  • J. A. Sáez-Nieto
    • 2
  • S. Valdezate
    • 2
  • R. H. Rodríguez-Pollán
    • 1
  • S. Lapeña
    • 3
  • F. Cachón
    • 1
  • F. Soriano
    • 4
  1. 1.Department of Clinical MicrobiologyComplejo Asistencial de León, SacylLeónSpain
  2. 2.Bacterial Taxonomy Laboratory, Servicio de BacteriologíaCentro Nacional de Microbiología, Instituto de Salud Carlos IIIMadridSpain
  3. 3.Department of PediatricsComplejo Asistencial de LeónLeónSpain
  4. 4.Department of Medical Microbiology and Antimicrobial ChemotherapyFundación Jiménez DíazMadridSpain

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