Preliminary investigations of the colonisation of upper respiratory tract tissues of infants using a paediatric formulation of the oral probiotic Streptococcus salivarius K12

  • D. A. Power
  • J. P. Burton
  • C. N. Chilcott
  • P. J. Dawes
  • J. R. TaggEmail author
Brief Report


A powder preparation of the oral probiotic Streptococcus salivarius K12 has been given to 19 young otitis media-prone children following a 3-day course of amoxicillin administered as a preliminary to ventilation tube placement. In two subjects, the use of strain K12 appeared to effect the expansion of an indigenous population of inhibitory S. salivarius. In other children, strain K12 colonisation extended beyond the oral cavity to also include the nasopharynx or adenoid tissue. The relatively low proportion (33%) of subjects that colonised was attributed to failure of the amoxicillin pre-treatment to sufficiently reduce the indigenous S. salivarius populations prior to dosing with strain K12 powder.


Infective Endocarditis Eric Profile SalB Enterobacterial Repetitive Intergenic Consensus Adenoid Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We gratefully acknowledge the assistance provided by nurse Rhonda Stafford in recruiting the patients.


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • D. A. Power
    • 1
  • J. P. Burton
    • 2
  • C. N. Chilcott
    • 2
  • P. J. Dawes
    • 3
  • J. R. Tagg
    • 1
    • 2
    Email author
  1. 1.Department of Microbiology and ImmunologyUniversity of OtagoDunedinNew Zealand
  2. 2.BLIS Technologies Ltd.DunedinNew Zealand
  3. 3.Otolaryngology and Head and Neck Surgery, Department of Medical and Surgical SciencesUniversity of OtagoDunedinNew Zealand

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