Outbreak of Achromobacter xylosoxidans pseudobacteremia in a neonatal care unit related to contaminated chlorhexidine solution
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Clusters and outbreaks of nosocomial infections occur frequently in neonatal care units (NCU). Achromobacter and Alcaligenes are emerging, infectious, gram-negative, oxidative, bacterial species that can affect immunocompromised patients and those with underlying illnesses. Epidemiological data suggest that water is the natural source of A. xylosoxidans and that most infections may be waterborne [1, 2, 3]. Holmes et al.  previously described clinical material as the source of this pathogen. In the literature, sporadic cases of bacteremia have appeared [3, 4, 5], but outbreaks in adults and newborns have also been reported [6, 7, 8, 9]. Some environmental sources contaminated with A. xylosoxidans and associated with nosocomial infections include swimming pools , respirators, humidifiers, incubators , deionized water , tap water, and chlorhexidine solutions [2, 7, 8].
Between January 2004 and June 2005, 58 cases of Achromobacter xylosoxidanscolonization or infection...
KeywordsCeftazidime Meropenem Colistin Chlorhexidine Cefoperazone
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