Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection
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- Seitsonen, E., Hynninen, M., Kolho, E. et al. Eur J Clin Microbiol Infect Dis (2006) 25: 261. doi:10.1007/s10096-006-0117-z
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Reported here are two cases of hantavirus pulmonary syndrome caused by Puumala virus infection, which rapidly resolved after initiation of corticosteroid treatment combined with continuous veno-venous hemodiafiltration. These cases emphasize the role of the inflammatory response in the pathogenesis of hantavirus pulmonary syndrome.