Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection

  • E. Seitsonen
  • M. Hynninen
  • E. Kolho
  • H. Kallio-Kokko
  • V. Pettilä
Concise Article


Reported here are two cases of hantavirus pulmonary syndrome caused by Puumala virus infection, which rapidly resolved after initiation of corticosteroid treatment combined with continuous veno-venous hemodiafiltration. These cases emphasize the role of the inflammatory response in the pathogenesis of hantavirus pulmonary syndrome.



This report was supported by a HUS research grant.


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • E. Seitsonen
    • 1
  • M. Hynninen
    • 2
  • E. Kolho
    • 3
  • H. Kallio-Kokko
    • 4
  • V. Pettilä
    • 2
  1. 1.Department of Anesthesiology and Intensive Care MedicineHelsinki University Central HospitalHelsinkiFinland
  2. 2.Department of Anesthesiology and Intensive Care MedicineHelsinki University Central HospitalHelsinkiFinland
  3. 3.Clinical Microbiology and Infectious DiseasesHelsinki University Central HospitalHelsinkiFinland
  4. 4.Department of Virology, Division of Clinical MicrobiologyHUSLAB -Helsinki University Central Hospital LaboratoryHelsinkiFinland

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