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Staphylococcus aureus positive for Panton-Valentine leukocidin genes but susceptible to methicillin in patients with furuncles

  • O. Nolte
  • H. Haag
  • A. Zimmerman
  • H. K. Geiss
Concise Article

Abstract

A total of 75 Staphylococcus aureus isolates obtained from patients with either recurrent skin abscesses or furuncles (n=48) or chronic infections from other body sites (n=27) were screened for the presence of the lukS-PV and lukF-PV genes encoding Panton-Valentine leukocidin. Significantly more isolates (70.8% vs. 7.4%, p<0.001) from patients suffering skin abscesses or furuncles were positive for lukS-PV and lukF-PV. These isolates belonged to the accessory gene regulator (agr) group Ia (9/48), group III (13/48), or group IV (19/48). In contrast with results of other investigations, none of the isolates positive for the Panton-Valentine leukocidin genes in this study exhibited methicillin resistance.

Keywords

Staphylococcus Aureus Methicillin Resistance Exfoliative Toxin Skin Abscess Accessory Gene Regulator 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgement

ON is supported by grant 13N8348 (BMBF, Germany)

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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • O. Nolte
    • 1
    • 3
  • H. Haag
    • 1
  • A. Zimmerman
    • 2
  • H. K. Geiss
    • 1
  1. 1.Department of Hygiene and Medical MicrobiologyHygiene-InstituteHeidelbergGermany
  2. 2.Department of VirologyHygiene-Institute, Im Neuenheimer Feld 324HeidelbergGermany
  3. 3.Department of MicrobiologyTechnical University of KaiserslauternKaiserslauternGermany

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