Staphylococcus aureus positive for Panton-Valentine leukocidin genes but susceptible to methicillin in patients with furuncles

Concise Article


A total of 75 Staphylococcus aureus isolates obtained from patients with either recurrent skin abscesses or furuncles (n=48) or chronic infections from other body sites (n=27) were screened for the presence of the lukS-PV and lukF-PV genes encoding Panton-Valentine leukocidin. Significantly more isolates (70.8% vs. 7.4%, p<0.001) from patients suffering skin abscesses or furuncles were positive for lukS-PV and lukF-PV. These isolates belonged to the accessory gene regulator (agr) group Ia (9/48), group III (13/48), or group IV (19/48). In contrast with results of other investigations, none of the isolates positive for the Panton-Valentine leukocidin genes in this study exhibited methicillin resistance.

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© Springer-Verlag 2005

Authors and Affiliations

  • O. Nolte
    • 1
    • 3
  • H. Haag
    • 1
  • A. Zimmerman
    • 2
  • H. K. Geiss
    • 1
  1. 1.Department of Hygiene and Medical MicrobiologyHygiene-InstituteHeidelbergGermany
  2. 2.Department of VirologyHygiene-Institute, Im Neuenheimer Feld 324HeidelbergGermany
  3. 3.Department of MicrobiologyTechnical University of KaiserslauternKaiserslauternGermany

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