Recurrent Rhodococcus equi infection with fatal outcome in an immunocompetent patient

  • P. Gabriels
  • H. Joosen
  • E. Put
  • J. Verhaegen
  • K. Magerman
  • R. Cartuyvels
Concise Article
  • 126 Downloads

Abstract

The majority of human Rhodococcus equi infections occur in immunocompromised hosts, especially those with AIDS, and infection in immunocompetent patients is rare. Reported here is a case of R. equi infection in a seemingly healthy patient with a very complicated course. Despite neurosurgery and prolonged antibiotic therapy the patient deceased.

References

  1. 1.
    Verville TH, Huycke MM, Greenfield RA, Fine DP, Kuhls TL, Slater LN (1994) Rhodococcus equi infections of humans. Medicine 73:119–132PubMedCrossRefGoogle Scholar
  2. 2.
    Weinstock DM, Brown AE (2002) Rhodococcus equi: an emerging pathogen. Clin Infect Dis 34:1379–1385PubMedCrossRefGoogle Scholar
  3. 3.
    Kedlaya I, Ing MB, Wong SS (2001) Rhodococcus equi infections in immunocompetent hosts: case report and review. Clin Infect Dis 32:e39–e46PubMedCrossRefGoogle Scholar
  4. 4.
    Prescott JF (1991) Rhodococcus equi: an animal and human pathogen. Clin Microbiol Rev 4:20–34PubMedGoogle Scholar
  5. 5.
    Takai S (1997) Epidemiology of Rhodococcus infections: a review. Vet Microbiol 56:167–176PubMedCrossRefGoogle Scholar
  6. 6.
    Barton MD, Hughes KL (1984) Ecology of Rhodococcus equi. Vet Microbiol 9:65–74PubMedCrossRefGoogle Scholar
  7. 7.
    Stackebrandt E, Rainy FA, Ward-Rainey NL (1997) Proposal for a new hierarchic classification system, Actinobacteria classis nov. Int J Syst Bacteriol 47:479–491CrossRefGoogle Scholar
  8. 8.
    Meyer DK, Reboli AC (2005) Other corynebacteria and Rhodococcus. In: Mandell GL, Bennett JE, Dolin R (eds) Principles and practice of infectious diseases. Churchill Livingstone, Philadelphia, pp 2472–2473Google Scholar
  9. 9.
    Hondalus MK, Mosser DM (1994) Survival and replication of Rhodococcus equi in macrophages. Infect Immun 62:4167–4175PubMedGoogle Scholar
  10. 10.
    Golub B, Falk G, Spink WW (1967) Lung abscess due to Corynebacterium equi: report of first human infection. Ann Intern Med 66:1174–1177PubMedGoogle Scholar
  11. 11.
    Corne P, Rajeebally I, Jonquet O (2002) Rhodococcus equi brain abscess in an immunocompetent patient. Scan J Infect Dis 34:300–302CrossRefGoogle Scholar
  12. 12.
    Takai S, Ohbushi S, Koike K, Tsubaki S, Oishi H, Kamada N (1991) Prevalence of virulent Rhodococcus equi in isolates from soil and feces of horses from horse-breeding farms with and without endemic infections. J Clin Microbiol 29:2887–2889PubMedGoogle Scholar
  13. 13.
    Nordmann P, Kerestedjian JJ, Ronco E (1992) Therapy of Rhodococcus equi disseminated infections in nude mice. Antimicrob Agents Chemother 36:1244–1248PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • P. Gabriels
    • 1
  • H. Joosen
    • 2
  • E. Put
    • 4
  • J. Verhaegen
    • 3
  • K. Magerman
    • 5
  • R. Cartuyvels
    • 5
  1. 1.Clinical Laboratory, Sint-Trudo HospitalSint-TruidenBelgium
  2. 2.Department of Internal MedicineSint-Trudo HospitalSint-TruidenBelgium
  3. 3.Department of MicrobiologyUniversity HospitalLeuvenBelgium
  4. 4.Department of NeurosurgeryVirga Jesse HospitalHasseltBelgium
  5. 5.Clinical LaboratoryVirga Jesse HospitalHasseltBelgium

Personalised recommendations