High prevalence of hepatitis B virus infection among tuberculosis patients with and without HIV in Rio de Janeiro, Brazil

  • C. A. Blal
  • S. R. L. Passos
  • C. Horn
  • I. Georg
  • M. G. Bonecini-Almeida
  • V. C. Rolla
  • L. De Castro
Concise Article

DOI: 10.1007/s10096-004-1272-8

Cite this article as:
Blal, C.A., Passos, S.R.L., Horn, C. et al. Eur J Clin Microbiol Infect Dis (2005) 24: 41. doi:10.1007/s10096-004-1272-8

Abstract

To determine the prevalence and exposure factors associated with hepatitis B infection in tuberculosis patients with and without HIV type 1 coinfection, the presence of hepatitis B virus serological markers was investigated in a retrospective study. The seroprevalence of hepatitis B virus in patients with tuberculosis only was 14.6%, and in tuberculosis patients coinfected with HIV it increased to 35.8%. In patients with HIV and tuberculosis coinfection, homosexuality constituted the principal exposure factor, while in tuberculosis patients without HIV, a gradual increase in hepatitis B virus seroprevalence was noted along with increasing age. The results demonstrate that hepatitis B infection is highly prevalent in tuberculosis patients in Brazil and suggest that a vaccination program for the general population should be considered in order to prevent further hepatitis B infections.

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • C. A. Blal
    • 1
  • S. R. L. Passos
    • 3
  • C. Horn
    • 1
  • I. Georg
    • 1
  • M. G. Bonecini-Almeida
    • 1
  • V. C. Rolla
    • 2
  • L. De Castro
    • 1
  1. 1.Departamento de Micro-Imuno-Parasitologia, Serviço de ImunologiaInstituto de Pesquisa Clínica Evandro Chagas, FiocruzRio de JaneiroBrazil
  2. 2.Departamento de EpidemiologiaInstituto de pesquisa Clínica Evandro Chagas, FiocruzRio de JaneiroBrazil
  3. 3.Departamento de Doenças InfecciosasInstituto de Pesquisa Clínica Evandro Chagas, FiocruzRio de JaneiroBrazil

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