Brucella Endocarditis: Clinical, Diagnostic, and Therapeutic Approach
- First Online:
- 258 Downloads
Brucella endocarditis is an uncommon focal complication of brucellosis. Presented here are 11 cases of Brucella endocarditis, all managed uniformly. The median duration of symptoms prior to diagnosis was 3 months. Five patients (45%) had underlying valvular damage, and in six (55%) endocarditis involved a normal valve. There was a predominance of aortic involvement (82%) and a high incidence of left ventricular failure (91%). Diagnostic suspicion was essential in order to test blood cultures correctly, which in this series were positive in 63% of the patients. Surgical treatment was undertaken in eight patients (72%), all with aortic involvement and left ventricular failure impossible to control with medication. One patient died during the immediate postoperative period. All the other patients received antibiotic therapy for 3 months, with no signs of relapse of the infection or malfunction of the prosthesis during a minimum follow-up period of 24 months.
- 1.Joint Food and Agriculture Organization (1986) Sixth report of the expert committee on brucellosis. WHO Monograph Series 740. World Health Organization, GenevaGoogle Scholar
- 3.Young EJ (1983) Human brucellosis. Rev Infect Dis 5:821–842Google Scholar
- 8.Alton GG, Jones LM, Pietz DE (1975) Laboratory techniques in brucellosis. WHO Monograph Series 55. WHO, Geneva, pp 1–163Google Scholar
- 9.Hausler WJ, Moyer NP, Holcomb LA (1980) Brucella. In: Lannette EH, Balows A, Hausler WJ. Shadomy HJ (eds) Manual of clinical microbiology, 4th edn. American Society for Microbiology, Washington DC, p 382Google Scholar