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Journal of Wood Science

, Volume 55, Issue 1, pp 27–31 | Cite as

Neuropharmacological activities of phytoncide released from Cryptomeria japonica

  • Wei-Wen Cheng
  • Chien-Tsong Lin
  • Fang-Hua Chu
  • Shang-Tzen Chang
  • Sheng-Yang Wang
Original Article

Abstract

Forest-air bathing and walking (shinrin-yoku) is beneficial to human heath. In this study the phytoncide (volatile compounds) released from Cryptomeria japonica plantation forest was characterized by using solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS). The main volatile compounds were α-pinene (19.35%), β-myrcene (16.98%), d-limonene (15.21%), and γ-muurolene (7.42%). Furthermore, the neuropharmacological activity of the essential oils from leaves of C. japonica (ECJ) was evaluated by several animal behavior tests. ECJ could prolong the sleeping phase of ICR (imprinting control region) mice in the pentobarbital-induced sleeping time model. Furthermore, both EJC and one of its monoterpenes, d-limonene, possessed potent anxiolytic and analgesic activities based on the results obtained from elevated plus maze and writhing tests. The volatile compounds released from C. japonica provide relaxing and stress-relieving effects on mice, and further study on the effect of phytoncide on humans is worthwhile.

Key words

Cryptomeria japonica Essential oil Neuropharmacological activities Phytoncide SPME 

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Copyright information

© The Japan Wood Research Society 2008

Authors and Affiliations

  • Wei-Wen Cheng
    • 1
  • Chien-Tsong Lin
    • 1
  • Fang-Hua Chu
    • 2
  • Shang-Tzen Chang
    • 2
  • Sheng-Yang Wang
    • 1
  1. 1.Department of Forestry/Core Lab of Plant Metabolomics in Biotechnology Development CenterNational Chung-Hsing UniversityTaichungTaiwan
  2. 2.School of Forestry and Resource ConservationNational Taiwan UniversityTaipeiTaiwan

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