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Combination of olfactory aplasia and congenital ocular motor apraxia: a previously unreported association

  • Hee Kyung Yang
  • Jae Hyoung KimEmail author
  • Jeong-Min HwangEmail author
Letter to the Editor
  • 15 Downloads

Dear Editor,

Congenital ocular motor apraxia is characterized by impaired horizontal voluntary saccades associated with compensatory head thrust [1]. Olfactory bulb hypoplasia is known to be associated with many syndromes such as Kallmann syndrome or CHARGE syndrome (Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary abnormalities, Ear anomalies and/or deafness) [2, 3]. We present two cases with a yet unreported association of congenital ocular motor apraxia and olfactory bulb aplasia.

Case report

Case 1

A 7-month-old boy presented with poor eye contact and poor grip of subjects. He was born at the age of 38 weeks with a body weight of 2.6 kg. He was diagnosed with hypothyroidism. Neurologic examination and electroencephalogram showed no other abnormal findings.

On ophthalmic examination, he fixed and followed a 5-in. object at near with either eye. He had esotropia of 15 prism diopters at near in the primary...

Notes

Compliance with ethical standards

The authors declare that the study has been performed in accordance with ethical standards laid down in the 1964 Declaration of Helsinki.

Conflict of interest

The authors declare that they have no conflicts of interest.

References

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Copyright information

© Fondazione Società Italiana di Neurologia 2019

Authors and Affiliations

  1. 1.Department of Ophthalmology, Seoul National University Bundang HospitalSeoul National University College of MedicineSeongnamSouth Korea
  2. 2.Department of Radiology, Seoul National University Bundang HospitalSeoul National University College of MedicineSeongnamSouth Korea

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