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One-year single-center experience with the Aperio thrombectomy device in large vessel occlusion in the anterior circulation: safety, efficacy, and clinical outcome

  • Marius Georg Kaschner
  • Daniel WeissEmail author
  • Christian Rubbert
  • John-Ih Lee
  • Michael Gliem
  • Sebastian Jander
  • Vivien Ivan
  • Bastian Kraus
  • Bernd Turowski
  • Julian Caspers
Original Article
  • 31 Downloads

Abstract

Background and purpose

The Aperio thrombectomy device (Aperio) is a stent retriever designed to achieve rapid and substantial flow restoration in acute ischemic stroke due to large-vessel occlusions (LVOs). We evaluated the safety and efficacy of the Aperio device and compared it with published data of established stent retrievers.

Methods

We retrospectively analyzed institutional data of consecutive stroke procedures in patients with LVO in the anterior circulation that were treated between January 2017 and December 2017 with the Aperio. Reperfusion rate regarding to the extended thrombolysis in cerebral infarction scale (eTICI), procedural times, early clinical outcome, and complications were documented.

Results

Eighty-two patients were treated by using the Aperio in LVO in the anterior circulation. Median age was 77 (± 12) years (w = 59.8%). Median Baseline National Institutes of Health Stroke Scale (NIHSS) score was 14. Fifty-three (64.6%) patients received intravenous thrombolysis. Successful recanalization (eTICI≥2b) was achieved in 85.3%. Mean time from groin puncture to final recanalization was 52.3 ± 34.8 min. Embolization to new territories occurred in one case. Symptomatic intracranial hemorrhage within 24 h was observed in six patients (7.3%). Twenty-eight (41.2%) out of 68 patients available for assessment of functional outcome at 3 months achieved favorable outcome (mRS 0–2).

Conclusion

The Aperio stent retriever mechanical thrombectomy device demonstrated high rates of successful reperfusion and a good safety profile in patients with acute ischemic stroke due to LVO in the anterior circulation.

Keywords

Ischemic stroke M1 segment occlusion Aperio thrombectomy device Thrombectomy Clinical outcome 

Notes

Contributors

All authors contributed to the conception of the work and the acquisition, analysis, and interpretation of data. They edited, revised, and finally approved the manuscript version to be published. They agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. BT received personal fees from Acandis outside the submitted work.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Patients were informed about the approach, benefit, and risks of the planned procedure in the emergency setting, and informed consent was obtained prior to intervention. Consent for retrospective data analysis was waived.

Ethics approval

The study was approved by the local ethics committees.

Provenance and peer review

Not commissioned; externally peer reviewed.

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Copyright information

© Fondazione Società Italiana di Neurologia 2019

Authors and Affiliations

  • Marius Georg Kaschner
    • 1
  • Daniel Weiss
    • 1
    Email author
  • Christian Rubbert
    • 1
  • John-Ih Lee
    • 2
  • Michael Gliem
    • 2
  • Sebastian Jander
    • 2
  • Vivien Ivan
    • 1
  • Bastian Kraus
    • 1
  • Bernd Turowski
    • 1
  • Julian Caspers
    • 1
  1. 1.Medical Faculty, Department of Diagnostic and Interventional RadiologyUniversity DuesseldorfDuesseldorfGermany
  2. 2.Medical Faculty, Department of NeurologyUniversity DuesseldorfDuesseldorfGermany

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