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Neurological Sciences

, Volume 40, Supplement 1, pp 191–192 | Cite as

ACT for migraine: effect of acceptance and commitment therapy (ACT) for high-frequency episodic migraine without aura: preliminary data of a phase-II, multicentric, randomized, open-label study

  • Licia GrazziEmail author
  • C. Bernstein
  • A. Raggi
  • E. Sansone
  • E. Grignani
  • M. Searl
  • P. Rizzoli
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Patients suffering from migraine without aura at high frequency (9/14 attacks per month) are particularly exposed to the risk of chronification and medication overuse.

The “cephalalgiophobia,” i.e., the fear of having a headache attack during a free period, is a common trait in these patients, and it may induce anxiety and depression. Moreover, it may induce an increase of medication intake and frequency of headache episodes. The result is a disabling condition, similar to that of patients suffering from chronic migraine, with the same clinical problems concerning treatment and management [1].

The treatment of this category of patients can be difficult and they need a multidisciplinary treatment to learn techniques to manage their pain alternatively to medications and before than a chronic migraine condition with medication overuse has been induced.

In recent years, non-pharmacological treatments have been proposed for treating patients with different forms of migraine and, among them,...

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

References

  1. 1.
    Giannini G, Zanigni S, Grimaldi D, Melotti R, Pierangeli G, Cortelli P, Cevoli S (2018) Cephalalgiaphobia as a feature of high-frequency migraine: a pilot study. J Headache Pain 14(49):1–6Google Scholar
  2. 2.
    Grazzi L, Raggi A, D’Amico D, Sansone E, Leonardi M, Andrasik F, Gucciardi A, Guido D, D’Andrea G (2018) A prospective pilot study of the effect on catecholamines of mindfulness training vs pharmacological prophylaxis in patients with chronic migraine and medication overuse headache. Cephalalgia:333102418801584.  https://doi.org/10.1177/0333102418801584
  3. 3.
    Hughes SL (2017) Acceptance and commitment therapy (ACT) for chronic pain: a systematic review and meta-analysis. Clin J Pain 33(6):552–568CrossRefPubMedGoogle Scholar

Copyright information

© Fondazione Società Italiana di Neurologia 2019

Authors and Affiliations

  • Licia Grazzi
    • 1
    Email author
  • C. Bernstein
    • 2
  • A. Raggi
    • 3
  • E. Sansone
    • 3
  • E. Grignani
    • 1
  • M. Searl
    • 2
  • P. Rizzoli
    • 2
  1. 1.Headache and Neuroalgology UnitNeurological Institute “C. Besta” IRCCS FoundationMilanItaly
  2. 2.J Graham Headache CenterBrigham and Women Faulkner HospitalBostonUSA
  3. 3.Neurology, Public Health and Disability UnitNeurological Institute “C. Besta” IRCCS FoundationMilanItaly

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