Bilateral trigeminal root entry zone enhancement in MOG-IgG-associated brainstem encephalitis
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Over the past few years, IgG antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) have attracted more attention in inflammatory demyelinating diseases of the central nervous system (CNS). Recent studies support the viewpoint that MOG-IgG-associated encephalomyelitis (MOG-EM) may be a disease entity in its own right, immunopathogenetically distinct from classic multiple sclerosis (MS) and AQP4-IgG-positive neuromyelitis optica spectrum disorders (NMOSD) . The incidence of brainstem involvement among patients with MOG-EM is estimated to be almost one-third . Up to our knowledge, the pontine trigeminal root entry zone (REZ) abnormality is frequently described in MS but extremely rare in MOG-EM . We herein describe an interesting neuroradiological finding of bilateral trigeminal REZ enhancement in a patient with MOG-IgG-associated brainstem encephalitis.
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