Auditory brainstem response to speech in children with high functional autism spectrum disorder
- 159 Downloads
Auditory brainstem response (ABR) provides useful information about the auditory brainstem pathway. However, there is little known about the subcortical speech processing in individuals with autism spectrum disorder (ASD). The aim of the present study was to investigate the subcortical speech processing in children with high functioning ASD. Twenty-eight children with ASD, with a mean age of 14.36 ± 1.86, and 28 typically developing (TD) children, with a mean age of 14.99 ± 1.92, were selected from Rofeydeh Rehabilitation Hospital (Tehran, Iran), and speech ABR (sABR) with a 40 ms synthetic /da/ syllable stimulus was recorded. There was no significant difference between the two groups in terms of age and IQ. Latencies of all waves in sABR and duration of V-A complex were significantly longer in children with ASD than in TD children. It was concluded that patients with ASD have deficits in the temporal neural encoding of speech at the brainstem level. Further studies are needed to generalize this result.
KeywordsAuditory brainstem response (ABR) Autism spectrum disorder (ASD)
Compliance with ethical standards
Ethics approval and consent to participate
All stages of this study were conducted with the informed consent of the participants and under the rules of the ethics committee of the University of Social Welfare and Rehabilitation Sciences.
Conflict of interest
The authors declare that they have no conflict of interest.
- 2.APA (2013) Diagnostic and Statistical Manual of Mental Disorders (DSM-5). 5 edn. American Psychiatric Publishing, ArlingtonGoogle Scholar
- 11.Eggermont JJ, Schmidt PH (1990) The auditory brainstem response. In: Evoked potential manual. Springer, pp 41–77Google Scholar
- 12.Roeser RJ, Valente M, Hosford-Dunn H (2007) AUDIOLOGY Diagnosis. Audiology, 2 edn. Thieme,Google Scholar
- 20.Akhoun I, Moulin A, Jeanvoine A, Ménard M, Buret F, Vollaire C, Scorretti R, Veuillet E, Berger-Vachon C, Collet L (2008) Speech auditory brainstem response (speech ABR) characteristics depending on recording conditions, and hearing status: an experimental parametric study. J Neurosci Methods 175(2):196–205CrossRefGoogle Scholar