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Intracranial arterial dolichoectasia and superficial siderosis associated to neurofibromatosis type 1: report of one case

  • Tirso González-Pinto
  • Tomás Pérez Concha
  • Ana Moreno Estébanez
Letter to the Editor
  • 5 Downloads

Dear Editor-in-Chief:

A 40-year-old man was admitted to the emergency department for acute onset of right hemiparesis and intense headache. He had a medical history of neurofibromatosis type 1 (NF1) and idiopathic generalized epilepsy with generalized onset tonic-clonic seizures. Both diagnoses had been made when the patient was just 5 years old. He had been seizure-free for the last 9 years. A computed tomography (CT) scan of the head and a CT angiography of cerebral and carotid arteries were performed. There were no established stroke or arterial occlusion, but a vertebrobasilar dolichoectasia and a saccular aneurysm of the cerebral media artery were found (Fig.  1a). Given the acute intense headache, a lumbar puncture was made, obtaining normal results. Due to high suspicion of a lacunar stroke, he was admitted to our stroke unit. A brain magnetic resonance imaging (MRI) showed a subacute left pontine ischemic stroke (Fig.  1b) and diffuse cerebral superficial siderosis (SS) (Fig.  2)....

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtained from all individual participants included in the study.

References

  1. 1.
    Pico F, Labreuche J, Amarenco P (2015) Pathophysiology, presentation, prognosis, and management of intracranial arterial dolichoectasia. Lancet Neurol 14(8):833–845CrossRefPubMedGoogle Scholar
  2. 2.
    Passero SG, Rossi S (2008) Natural history of vertebrobasilar dolichoectasia. Neurology 70(1):66–72CrossRefPubMedGoogle Scholar
  3. 3.
    Del Brutto VJ, Ortiz JG, Biller J (2017) Intracranial arterial dolichoectasia. Front Neurol 8:344CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Fellgiebel A, Muller MJ, Ginsberg L (2006) CNS manifestations of Fabrys disease. Lancet Neurol 5:791–795CrossRefPubMedGoogle Scholar
  5. 5.
    Hensel O, Hanisch F, Stock K, Stoevesandt D, Deschauer M, Müller T (2015) Morphology and function of cerebral arteries in adults with Pompe disease. JIMD Reports 20:27–33CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Giannantoni NM, Broccolini A, Frisullo G, Pilato F, Profice P, Morosetti R, di Lella G, Zampino G, Marca GD (2015) Neurofibromatosis type 1 associated with vertebrobasilar dolichoectasia and pontine ischemic stroke. J Neuroimaging 25(3):505–506CrossRefPubMedGoogle Scholar
  7. 7.
    Kumar N (2012) Beyond superficial siderosis: introducing “duropathies”. Neurology 78:1992–1999CrossRefPubMedGoogle Scholar
  8. 8.
    Zerna C, Modi J, Bilston L, Shoamanesh A, Coutts SB, Smith EE (2016) Cerebral microbleeds and cortical superficial siderosis in patients presenting with minor cerebrovascular events. Stroke 47(9):2236–2222CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Servicio de NeurologíaHospital Universitario de CrucesBarakaldoSpain

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