Bulleidia extructa and Actinomyces israelii infections in a patient with brain abscess
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A brain abscess is defined as an area of parenchymal infection containing pus, encapsulated by a vascularized membrane . The causes of infection are often attributed to hematogenous or contiguous spread, neurosurgical procedures, and penetrating head trauma . Both aerobic and anaerobic organisms have been identified as causes of brain abscesses . Streptococci are the most frequently identified bacteria among aerobic pathogens, whereas Bacteroides fragilis and Peptostreptococcus are the most common anaerobic species isolated from brain abscess . Streptococcus, Actinomyces, Peptostreptococcus, and Fusobacterium species are commonly implicated in brain abscesses of odontogenic origin . Actinomyces israelii, Actinomyces meyeri, and Actinomyces odontolyticus have been reported to cause brain abscesses among Actinomyces species .
Bulleidia extructa is an anaerobic non-sporing Gram-positive bacillus which was isolated from human periodontitis in 2000 . The...
The authors would like to thank Dr. Kenji Sakai of the Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences for helpful comments, Dr. Ryoichi Takahashi of the Department of Neurology, Toyama Prefectural Central Hospital for helpful clinical advice on the patient, and Masahiko Nakamura of Toyama Prefectural Central Hospital for providing technical assistance.
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Conflict of interest
The authors declare that they have no conflict of interest.
Informed consent was obtained from all individual participants included in the study.