Neurological Sciences

, Volume 39, Supplement 1, pp 165–166 | Cite as

Commiphora myrra, alternative treatment in migraine prophylaxis: open label prospective pilot study

  • Maria Clara ToniniEmail author
  • Laura Giordano

Many substances extracted from minerals, plants, microorganisms, and animals are defined as nutraceuticals because they have a preventive therapeutic value on health; some of them, such as magnesium, riboflavin, coenzyme Q10, Tanacetum parthenium, Petasites hybridus, gingolide, for their particular biochemical, vascular, and neuroreceptoral mechanisms have been used in the prophylaxis of primary headaches, either alone or in combination products. The European, American, and Canadian therapeutic guidelines have provided the recommendations and evidence for their use in migraine prophylaxis [1].

Recently, attention has been given to Myrrh, a resin derived from the Commiphora myrra of the Burseraceae family (patented MyrLiq formula), which for the high content of furanodienes, possesses anti-inflammatory, analgesic, and anesthetic properties [2, 3].

Myrrh is proposed in combination with other migraine prevention nutraceuticals, such as Gingko biloba, riboflavin, and coenzyme Q10, already...


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Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Rajapakse T, Pringsheim T (2016) Nutraceuticals in migraine: a summary of existing guidelines for use. Headache 56(4):808–816CrossRefPubMedGoogle Scholar
  2. 2.
    Shulan S, Wang T, Duan JA et al (2011) Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha. J Ethnopharmacol 134:251–258CrossRefGoogle Scholar
  3. 3.
    Germano A, Occhipinti A, Barbero F and Maffei ME (2017) A pilot study on bioactive constituents and analgesic effects of MyrLiq, a Commiphora myrra extract with a high furanodiene content. Biomed Res Int Article ID 3804356.

Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Center for the Diagnosis and Treatment of HeadacheClinica San Carlo Paderno DugnanoPaderno DugnanoItaly
  2. 2.Humanitas Clinical and Research CenterBiostatistic UnitRozzanoItaly

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