Asterixis commonly occurs in a patient with metabolic encephalopathy, whereas focal brain lesions such as thalamus, cerebellum, or frontal area also cause focal or unilateral asterixis in the arms. We report a novel case of asterixis in the leg after unilateral anterior cerebral artery territory infarction. A 76-year-old man was admitted with sudden-onset mild right leg weakness and postural instability due to knee buckling. He was diagnosed with ischemic stroke in the left prefrontal area and cingulated gyrus by brain magnetic imaging. Needle electromyography of the right vastus lateralis muscle while standing showed intermittent periods of EMG silence, consistent with asterixis. There were no abnormal involuntary movements in the upper extremities. This case suggests that gait disturbance or postural instability after structural lesions in the prefrontal area may be directly related to asterixis in the leg, not in the arm associated with postural failure.
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Ghika-Schmid F, Ghika J, Regli F et al (1997) Hyperkinetic movement disorders during and after acute stroke: the Lausanne Stroke Registry. J Neurol Sci 146(2):109–116
Kim JS (2001) Involuntary movements after anterior cerebral artery territory infarction. Stroke 32(1):258–261
Mehanna R, Jankovic J (2013) Movement disorders in cerebrovascular disease. Lancet Neurol 12(6):597–608
Bansil S, Prakash N, Kaye J et al (2012) Movement disorders after stroke in adults: a review. Tremor Other Hyperkinet Mov (N Y) 2
Young RR, Shahani BT (1986) Asterixis: one type of negative myoclonus. Adv Neurol 43:137–156
Matsumoto H, Hashida H, Ugawa Y (2014) Unilateral asterixis caused by an internal capsule lesion. Intern Med 53(4):341–342
Kim JS (2001) Asterixis after unilateral stroke: lesion location of 30 patients. Neurology 56(4):533–536
Siniscalchi A, Gallelli L, Di Benedetto O et al (2012) Asterixis as a presentation of cerebellar ischemic stroke. West J Emerg Med 13(6):507–508
Inoue M, Kojima Y, Mima T et al (2012) Pathophysiology of unilateral asterixis due to thalamic lesion. Clin Neurophysiol 123(9):1858–1864
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Sunwoo, M.K., Jang, H., Roh, S.Y. et al. Asterixis in the leg induced by anterior cerebral artery infarction. Neurol Sci 37, 979–981 (2016). https://doi.org/10.1007/s10072-016-2486-0
- Movement disorder
- Anterior cerebral artery territory infarction