Neurological Sciences

, Volume 37, Issue 2, pp 181–189 | Cite as

Aspirin resistance and other aspirin-related concerns

  • Gaoyu Cai
  • Weijun Zhou
  • Ya Lu
  • Peili Chen
  • Zhongjiao Lu
  • Yi FuEmail author
Review Article


Aspirin is a widely used medication and has become a cornerstone for treating cardiovascular disease. Aspirin can significantly reduce the incidence of cardiovascular ischemic events, recurrence and mortality, thereby improving the long-term prognosis of patients. However, there has been a staggering increase in the volume of literature addressing the issue of so-called “aspirin resistance” in recent years, and for some patients, it is difficult to avoid adverse reactions to aspirin. In this review, we present both the historical aspects of aspirin use and contemporary developments in its clinical use.


Aspirin Clinical use Resistance phenomenon Adverse effects 


Compliance with ethical standards

Conflict of interest



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Copyright information

© Springer-Verlag Italia 2015

Authors and Affiliations

  • Gaoyu Cai
    • 1
  • Weijun Zhou
    • 2
  • Ya Lu
    • 3
  • Peili Chen
    • 2
  • Zhongjiao Lu
    • 1
  • Yi Fu
    • 1
    Email author
  1. 1.Department of Neurology and Institute of NeurologyRui Jin Hospital, School of Medicine, Shanghai Jiao Tong UniversityShanghaiChina
  2. 2.Department of EmergencyRui Jin Hospital, School of Medicine, Shanghai Jiao Tong UniversityShanghaiChina
  3. 3.Shanghai Wusong Street Community Health Service CenterShanghaiChina

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