Neurological Sciences

, Volume 36, Issue 12, pp 2185–2190 | Cite as

Normative data for the ACE-R in an Italian population sample

  • Martina PigliautileEmail author
  • Francesca Chiesi
  • Sonia Rossetti
  • Manuela Conestabile della Staffa
  • Monica Ricci
  • Stefano Federici
  • Dora Chiloiro
  • Caterina Primi
  • Patrizia Mecocci
Original Article


The Addenbrooke’s Cognitive Examination Revised (ACE-R) is a brief cognitive screening instrument also proposed to detect mild cognitive impairment, a high-risk condition for Alzheimer’s disease and other forms of dementia. In this study, we report normative data on the ACE-R-Italian version, collected on a sample of 264 Italian healthy subjects aging between 60 and 93 years, and with a formal education from 1 to 19 years. The global normal cognition was established in accordance with the Italian version of the Mini–Mental State Examination score and with exclusion criteria derived by a consensus process. Linear regression analysis was performed to evaluate the effect of age, gender, and education on the ACE-R total performance score. We provide correction grids to adjust raw scores and equivalent scores with cut-off value to allow comparison between ACE-R performance and others neuropsychological test scores that can be administered to the same subject.


ACE-R Normative data Screening Dementia 



The authors acknowledge the control subjects and all the physicians at the Santa Maria della Misericordia Hospital in Perugia and the psychologists at the Clinical Psychology and Psychotherapy Adult and Developmental Ages in Taranto for their involvement in this study.

Compliance with ethical standards

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.


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Copyright information

© Springer-Verlag Italia 2015

Authors and Affiliations

  • Martina Pigliautile
    • 1
    Email author
  • Francesca Chiesi
    • 2
  • Sonia Rossetti
    • 3
  • Manuela Conestabile della Staffa
    • 1
  • Monica Ricci
    • 4
  • Stefano Federici
    • 5
  • Dora Chiloiro
    • 3
  • Caterina Primi
    • 2
  • Patrizia Mecocci
    • 1
  1. 1.Section of Gerontology and Geriatrics, Department of MedicineUniversity of PerugiaPerugiaItaly
  2. 2.Department of Neuroscience, Psychology, Drug Research, and Child’s Health (NEUROFARBA)-Section of PsychologyUniversity of FlorenceFlorenceItaly
  3. 3.Unit of Clinical PsychologyAzienda Sanitaria LocaleTarantoItaly
  4. 4.ARC Centre of Excellence in Cognition and its DisordersMacquarie UniversitySydneyAustralia
  5. 5.Social and Human Sciences and Education, Department of PhilosophyUniversity of PerugiaPerugiaItaly

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