Neurological Sciences

, Volume 36, Issue 11, pp 2137–2138 | Cite as

Spontaneous disappearance of Holmes’ tremor in a patient with a midbrain cavernous hemangioma

  • Jung Han Yoon
  • Seok Woo Yong
  • Jin Soo Lee
Letter to the Editor

Dear Editor,

Holmes’ tremor is an uncommon movement disorder characterized by a combination of resting, postural and kinetic tremors, and is difficult to treat. We observed a spontaneous disappearance of Holmes’ tremor caused by a midbrain cavernous hemangioma, along with detailed serial neuroimaging studies.

A 54-year-old right-handed man presented to our clinic complaining of the gradual onset of a left arm tremor that prevented him from holding a cup or using a spoon during a meal. He had no personal or family history of head trauma. Upon examination, the patient had a 4- to 5-Hz resting tremor and severe postural and kinetic tremors in his left arm. His muscle power and deep tendon reflex were normal, but a sensory examination revealed that light touch, pinprick, and vibratory sensations were diminished on his left face, extremities, and body. Although the patient exhibited partial right third cranial nerve palsy with preservation of the pupil reflex and adduction palsy of the...


Holmes’ tremor Midbrain tremor Cavernous hemangioma 


Conflict of interest



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Copyright information

© Springer-Verlag Italia 2015

Authors and Affiliations

  1. 1.Department of NeurologyAjou University School of MedicineSuwon-siSouth Korea

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