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Neurological Sciences

, Volume 33, Issue 4, pp 831–838 | Cite as

Validation of a home environment test battery for supporting assessments in advanced Parkinson’s disease

  • Jerker WestinEmail author
  • Mauro Schiavella
  • Mevludin Memedi
  • Dag Nyholm
  • Mark Dougherty
  • Angelo Antonini
Original Article

Abstract

Test sequences in a test battery for Parkinson’s disease patients, consisting of self-assessments and motor tests, were carried out repeatedly in a telemedicine setting, during week-long test periods and results were summarized in an ‘overall score’. 35 patients in stable and fluctuating conditions (15 age- and gender-matched pairs) used the test battery for 1 week, and were then assessed with UPDRS and PDQ-39. This procedure was repeated 1 week later, without treatment changes. Reliability was assessed by intraclass correlation coefficients and Cronbach’s alpha. Convergent validity was assessed by Spearman rank correlations and known-groups’ validity, by the Mann–Whitney test. According to anonymous usability questionnaires, the patients could easily complete the tasks. Median compliance (93%) and test–retest reliability (0.88) were good. The correlations between overall score and total UPDRS (−0.64) and PDQ-39 (−0.72) were adequate. Median overall score was 18% better in the stable compared to the fluctuating group (p = 0.0014).

Keywords

Parkinson’s disease Motor fluctuations Telemedicine Self-assessment Motor tests Validity 

Notes

Acknowledgments

This work was performed in the framework of the MOVISTAR project, funded by the Swedish Knowledge Foundation, Solvay Pharmaceuticals, Allschwil, Switzerland, Nordforce Technology, Stockholm Sweden and the authors’ respective institutions. Authors Westin, Nyholm and Dougherty have filed a patent application and started a company for supplying the test battery described in this article.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Jerker Westin
    • 1
    • 4
    Email author
  • Mauro Schiavella
    • 2
  • Mevludin Memedi
    • 1
  • Dag Nyholm
    • 3
  • Mark Dougherty
    • 1
  • Angelo Antonini
    • 2
    • 5
  1. 1.Academy of Industry and Society, Computer ScienceDalarna UniversityBorlängeSweden
  2. 2.Parkinson Institute, Istituti Clinici di PerfezionamentoMilanItaly
  3. 3.Department of Neuroscience, NeurologyUppsala UniversityUppsalaSweden
  4. 4.Department of Medical Sciences, Biomedical Informatics and EngineeringUppsala UniversityUppsalaSweden
  5. 5.Department for Parkinson’s diseaseIRCCS San CamilloVeniceItaly

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