Neurological Sciences

, Volume 33, Issue 2, pp 445–448 | Cite as

Transient contrast encephalopathy after carotid angiography mimicking diffuse subarachnoid haemorrhage

  • Stamatia Potsi
  • Danai Chourmouzi
  • Anestis Moumtzouoglou
  • Aikaterini Nikiforaki
  • Kostas Gkouvas
  • Antonios Drevelegas
Case Report

Abstract

Neurotoxicity caused by intraarterial injection of low-dose low osmolar, iodinated contrast agents during radiologic studies is an extremely rare adverse event. Contrast medium induced disruption of the blood–brain barrier and a direct neurotoxic effect by contrast media have been proposed as a potential mechanism of neurotoxicity. This report describes an unusual case of transient neurotoxicity following diagnostic angiography mimicking clinically and radiologically subarachnoid hemorrhage. The patient recovered without any intervention after 4 days of conservative treatment.

Keywords

Cerebral angiography Contrast encephalopathy Computed tomography 

References

  1. 1.
    Davis K, Kennedy JW, Kemp HG et al (1979) Complications of coronary arteriography from the collaborative study of coronary artery surgery (CASS). Circulation 59:1105–1111PubMedGoogle Scholar
  2. 2.
    De Bono D (1993) Complications of diagnostic cardiac catheterization: results from 34, 041 patients in the United Kingdom confidential enquiry into cardiac catheterization complications. Br Heart J 70:297–300PubMedCrossRefGoogle Scholar
  3. 3.
    Dangas G, Monsein LH, Laureno R et al (2001) Transient contrast encephalopathy after carotid artery stenting. J Endovasc Ther 8:111–113PubMedCrossRefGoogle Scholar
  4. 4.
    Studdard WE, Davis DO, Young SW (1981) Cortical blindness after cerebral angiography. J Neurosurg 54:240–244PubMedCrossRefGoogle Scholar
  5. 5.
    Utz R, Ekholm SE, Isaac L et al (1988) Local blood–brain barrier penetration following systemic contrast medium administration. Acta Radiol 29:237–242PubMedCrossRefGoogle Scholar
  6. 6.
    Frontera JA, Pile-Spellman J, Mohr JP (2007) Contrast-induced neurotoxicity and selective cortical injury. Cerebrovasc Dis 24:148–151PubMedGoogle Scholar
  7. 7.
    Saigal G, Bhatia R, Bhatia S, Wakhloo A (2004) MR findings of cortical blindness following cerebral angiography: is this entity related to posterior reversible leukoencephalopathy? Am J Neuroradiol 25:252–256PubMedGoogle Scholar
  8. 8.
    Guimaraens L, Vivas E, Fonnegra A et al (2010) Transient encephalopathy from angiographic contrast: a rare case. Complication in neurointerventional procedures. Cardiovasc Intervent Radiol 33:383–388PubMedCrossRefGoogle Scholar
  9. 9.
    Fang H, Kuo Y, Wu C (2009) Transient contrast encephalopathy after carotid artery stenting mimicking diffuse subarachnoid hemorrhage: a case report. Catheter Cardiovasc Interv 73:123–126PubMedCrossRefGoogle Scholar
  10. 10.
    Ko DY (2000) Contrast agent neurotoxicity presenting as subarachnoid hemorrhage. Neurology 54(4):1014–1015PubMedGoogle Scholar
  11. 11.
    Velden J, Milz P, Winkler F et al (2003) Nonionic contrast neurotoxicity after coronary angiography mimicking subarachnoid hemorrhage. Eur Neurol 49(4):249–251PubMedCrossRefGoogle Scholar
  12. 12.
    Landtblom AM, Boivie J, Fridriksson S et al (2006) Thunderclap headache mostly a benign condition. Investigation guidelines-subarachnoid hemorrhage should be excluded. Lakartidningen 103(37):2632–2634, 2637Google Scholar
  13. 13.
    Lam DH (2008) Subarachnoid haematoma after spinal anaesthesia mimicking transient radicular irritation: a case report and review. Anaesthesia 63(4):423–427PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Stamatia Potsi
    • 1
  • Danai Chourmouzi
    • 1
  • Anestis Moumtzouoglou
    • 1
  • Aikaterini Nikiforaki
    • 1
  • Kostas Gkouvas
    • 2
  • Antonios Drevelegas
    • 3
  1. 1.Radiology DepartmentInterbalkan Medical HospitalThessalonikiGreece
  2. 2.Department of Vascular SurgeryInterbalkan Medical HospitalThessalonikiGreece
  3. 3.Department of Diagnostic RadiologyAHEPA University HospitalThessalonikiGreece

Personalised recommendations