Neurological Sciences

, Volume 32, Issue 6, pp 1209–1212

VGCC antibody-positive paraneoplastic cerebellar degeneration presenting with positioning vertigo

  • Emina Ogawa
  • Ryuji Sakakibara
  • Kengo Kawashima
  • Tomoe Yoshida
  • Masahiko Kishi
  • Fuyuki Tateno
  • Manabu Kataoka
  • Tatsuo Kawashima
  • Masahiko Yamamoto
Brief Communication

DOI: 10.1007/s10072-011-0648-7

Cite this article as:
Ogawa, E., Sakakibara, R., Kawashima, K. et al. Neurol Sci (2011) 32: 1209. doi:10.1007/s10072-011-0648-7

Abstract

A 70-year-old woman developed paraneoplastic cerebellar degeneration (PCD) due to P/Q-type and N-type voltage-gated calcium channel antibodies and small cell lung cancer, the main clinical manifestations of which were severe positioning vertigo and vomiting. Loss of the visual suppression of caloric nystagmus, spontaneous downbeat nystagmus, periodic alternating nystagmus, and positioning vertigo in our patient most probably corresponds to the cerebellar flocculus/paraflocculus lesion caused by PCD.

Keywords

Subacute cerebellar degeneration Paraneoplastic syndrome Positional vertigo 

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Emina Ogawa
    • 1
  • Ryuji Sakakibara
    • 1
  • Kengo Kawashima
    • 2
  • Tomoe Yoshida
    • 3
  • Masahiko Kishi
    • 1
  • Fuyuki Tateno
    • 1
  • Manabu Kataoka
    • 4
  • Tatsuo Kawashima
    • 2
  • Masahiko Yamamoto
    • 3
  1. 1.Neurology Division, Department of Internal Medicine, Sakura Medical CenterToho UniversitySakuraJapan
  2. 2.Respiratory Disease and Allergy Division, Department of Internal Medicine, Sakura Medical CenterToho UniversitySakuraJapan
  3. 3.Department of Otorhinolaryngology, Sakura Medical CenterToho UniversitySakuraJapan
  4. 4.Clinical Physiology Unit, Sakura Medical CenterToho UniversitySakuraJapan

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