Neurological Sciences

, Volume 32, Supplement 1, pp 85–88 | Cite as

Migraine and depression: common pathogenetic and therapeutic ground?

  • F. Moschiano
  • D. D’Amico
  • I. Canavero
  • I. Pan
  • G. Micieli
  • G. Bussone
Migraine and Depression


Migraine and depression are recognized as comorbid disorders on the basis of several epidemiological data and on the possibility of shared mechanisms. On the other hand, there is a lack of studies concerning therapeutic strategies in patients with this comorbidity. The aim of this paper is to briefly review the literature about the migraine and depression comorbidity and on the putative common neurobiological mechanisms, as well to discuss the possible therapeutic options in treating patients with both disorders.


Migraine Depression Comorbidity Pathogenesis Therapy 


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • F. Moschiano
    • 1
  • D. D’Amico
    • 2
  • I. Canavero
    • 1
  • I. Pan
    • 1
  • G. Micieli
    • 1
  • G. Bussone
    • 2
  1. 1.National Institute of NeurologyIRCCS C. Mondino FoundationPaviaItaly
  2. 2.Headaches Unit, Neurological Institute “C. Besta” IRCCS FoundationMilanItaly

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