Neurological Sciences

, Volume 31, Issue 6, pp 807–811 | Cite as

Long survival and clinical stability in Marburg’s variant multiple sclerosis

  • Marco TurattiEmail author
  • Alberto Gajofatto
  • Francesca Rossi
  • Marcella Vedovello
  • Maria Donata Benedetti
Case Report


Marburg’s variant multiple sclerosis (MS) is an acute and aggressive atypical form of MS, leading frequently to death in few months. A 32-year-old man with motor and sensory symptoms suggestive of acute myelopathy, rapidly followed by cerebellar dysfunction and consciousness impairment. Clinical, laboratory and radiological evaluations suggested a central nervous system demyelinating disease. The diagnosis was Marburg’s variant MS, usually leading to death in short time. He underwent different treatments, including steroids, cyclophosphamide, plasma exchange and lastly interferon-beta. The patient reached clinical stability with severe residual disability, persistent after 3 years from onset. This observation suggests that subjects with Marburg’s MS might reach long clinical stability.


Long survival Marburg’s variant Multiple sclerosis 


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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Marco Turatti
    • 1
    Email author
  • Alberto Gajofatto
    • 1
  • Francesca Rossi
    • 1
  • Marcella Vedovello
    • 1
  • Maria Donata Benedetti
    • 1
  1. 1.Section of Neurology, Department of Neurological and Vision SciencesUniversity of VeronaVeronaItaly

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