Neurological Sciences

, Volume 31, Issue 2, pp 133–136

Dementia and capsular genu ischemia in patients with severe bacterial meningitis

  • Makoto Naito
  • Ken Johkura
  • Takayuki Momoo
  • Tamaki Nomiya
  • Yosuke Kudo
  • Yoshiyuki Kuroiwa
Original Article

DOI: 10.1007/s10072-009-0168-x

Cite this article as:
Naito, M., Johkura, K., Momoo, T. et al. Neurol Sci (2010) 31: 133. doi:10.1007/s10072-009-0168-x

Abstract

Infarction in the genu of the internal capsule causes dementia that is characterized by abulia, lethargy and memory loss without obvious motor palsy (capsular genu syndrome). We found infarction or decreased cerebral blood flow in the genu of the internal capsule in 6 of 13 patients with severe bacterial meningitis. Four of these six patients developed post-meningitis dementia, characterized by abulia, lethargy, and memory loss. Of 24 patients with viral meningitis, none developed capsular genu ischemia or post-meningitis dementia. In patients with severe bacterial meningitis, capsular genu ischemia may play some role in the development of post-meningitis dementia. In patients with viral meningitis, absence of such ischemia may explain, at least in a part, the rarity of post-meningitis dementia.

Keywords

Bacterial meningitis Capsular genu infarction Dementia SPECT 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Makoto Naito
    • 1
  • Ken Johkura
    • 2
  • Takayuki Momoo
    • 2
  • Tamaki Nomiya
    • 2
  • Yosuke Kudo
    • 2
  • Yoshiyuki Kuroiwa
    • 3
  1. 1.Department of NeurologyKanagawa Prefectural Ashigara Kami HospitalMatsuda-choJapan
  2. 2.Department of NeurologyHiratsuka Kyosai HospitalHiratsukaJapan
  3. 3.Department of NeurologyYokohama City University School of MedicineYokohamaJapan

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