Neurological Sciences

, Volume 29, Supplement 2, pp 238–240

Different types of fatigue in patients with facioscapulohumeral dystrophy, myotonic dystrophy and HMSN-I. Experienced fatigue and physiological fatigue

  • Joke S. Kalkman
  • Machiel J. Zwarts
  • Maartje L. Schillings
  • Baziel G. M. van Engelen
  • Gijs Bleijenberg
Updates in Clinical Neurology

DOI: 10.1007/s10072-008-0949-7

Cite this article as:
Kalkman, J.S., Zwarts, M.J., Schillings, M.L. et al. Neurol Sci (2008) 29(Suppl 2): 238. doi:10.1007/s10072-008-0949-7
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Abstract

Although fatigue is a common symptom in neuromuscular disorders, little is known about different types of fatigue. Sixty-five FSHD, 79 adult-onset MD and 73 HMSN type I patients were studied. Experienced fatigue was assessed with the CIS-fatigue subscale. Physiological fatigue was measured during a 2-min sustained maximal voluntary contraction of the biceps brachii muscle using the twitch interpolation technique to assess central activation failure (CAF) and peripheral fatigue. Experienced fatigue, CAF and peripheral fatigue appeared to be predominantly separate types of fatigue.

Keywords

Experienced fatigue Central activation failure Peripheral fatigue Neuromuscular disorders 

Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Joke S. Kalkman
    • 1
    • 2
  • Machiel J. Zwarts
    • 3
  • Maartje L. Schillings
    • 3
  • Baziel G. M. van Engelen
    • 4
  • Gijs Bleijenberg
    • 2
  1. 1.Department of Medical PsychologyRadboud University Nijmegen Medical CentreNijmegenThe Netherlands
  2. 2.Expert Centre Chronic FatigueRadboud University Nijmegen Medical CentreNijmegenThe Netherlands
  3. 3.Department of Clinical Neurophysiology, Institute of NeurologyRadboud University Nijmegen Medical CentreNijmegenThe Netherlands
  4. 4.Neuromuscular Centre Nijmegen, Institute of NeurologyRadboud University Nijmegen Medical CentreNijmegenThe Netherlands

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