Neurological Sciences

, Volume 29, Supplement 2, pp 216–217

Interferon-beta responders and non-responders. A biological approach

Multiple Sclerosis: The Management of Non-Responders

DOI: 10.1007/s10072-008-0941-2

Cite this article as:
Bertolotto, A. & Gilli, F. Neurol Sci (2008) 29(Suppl 2): 216. doi:10.1007/s10072-008-0941-2


The therapeutic benefits of interferon-beta are limited, as some patients with multiple sclerosis (MS) do not respond to therapy. Based on their biological characteristics, non-responsive patients can be divided into three subgroups: genetic, pharmacological and pathogenetic non-responders. In order to tailor the best treatment in both newly diagnosed MS patients and those already receiving treatment, the neurologist must carefully consider the risk of treating non-responders.


Interferon Responder and non-responder Multiple sclerosis 

Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  1. 1.Centro Riferimento Regionale Sclerosi Multipla (CRESM) & Neurobiologia ClinicaAOU S. Luigi GonzagaOrbassanoItaly

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