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Neurological Sciences

, Volume 27, Supplement 2, pp s179–s182 | Cite as

Pathophysiological mechanisms of neuropathic pain

  • A. Truini
  • G. Cruccu
MECHANISMS AND TREATMENT OF NEUROPATHIC PAIN

Abstract

It is largely acknowledged that multiple and complex pathophysiological mechanisms may be at play in neuropathic pain. This short review summarises the current understanding of pathophysiology of neuropathic pain and focuses on how symptoms translate in mechanisms.

Key words

Peripheral sensitization Central sensitization Nociceptive pathway 

Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  1. 1.EFNS Panel on Neuropathic Pain and Department of Neurological Sciences“La Sapienza” UniversityRomeItaly

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