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Neurological Sciences

, Volume 27, Supplement 1, pp s40–s43 | Cite as

Parkinson’s disease and dementia

  • A. PadovaniEmail author
  • C. Costanzi
  • N. Gilberti
  • B. Borroni
NON-ALZHEIMER DEMENTIAS

Abstract

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, affecting about 1% of the population over the age of 60. In addition to motor abnormalities, there are several non-motor signs and symptoms that may create a considerable burden for patients and care-givers. Dementia is common and affects approximately 40% of PD patients during the course of the disease, the risk for the development of dementia being 6 times higher than in non-PD age-matched controls. In most cases, PD patients with dementia (PDD) display a dysexecutive syndrome and visuospatial deficits, while memory is relatively unaffected. The overlap between PDD and dementia with Lewy bodies suggests that they likely share similar underlying neuropathological processes.

Key words

Parkinson disease Dementia Lewy bodies Alzheimer disease Cognitive functioning Neuroimaging 

Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • A. Padovani
    • 1
    Email author
  • C. Costanzi
    • 1
  • N. Gilberti
    • 1
  • B. Borroni
    • 1
  1. 1.Department Medical and Surgical Sciences, Institute of NeurologyUniversity of BresciaBresciaItaly

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