Antagonistic and antioxidant effect of probiotic Weissella cibaria JW15

  • Hyung-Seok Yu
  • Na-Kyoung Lee
  • Ae-Jin Choi
  • Jeong-Sook Choe
  • Chun Ho Bae
  • Hyun-Dong PaikEmail author


The objective of this study was to evaluate the functional properties of Weissella cibaria JW15 (JW15) by investigating its antagonistic and antioxidant activities. Lactobacillus rhamnosus GG (LGG) was used for comparison as a reference strain. JW15 inhibited the growth of pathogenic bacteria (Listeria monocytogenes, Salmonella Typhimurium, S. Enteritidis, and Escherichia coli). Compared to LGG, JW15 showed rapid organic acid production, with the amounts of lactic and acetic acids being lower and higher, respectively. In addition, JW15 significantly inhibited intestinal epithelial adherence in the tested pathogens. JW15 exhibited antioxidant effects by scavenging radicals including DPPH, ABTS, and hydroxyl radicals, and inhibiting lipid peroxidation. JW15 exhibited significant antagonistic and antioxidant activities compared to LGG in the tested assay (p < 0.05). The results suggested that JW15 might possess a potential for amelioration of disorders induced by pathogenic bacteria or oxidative stress.


Weissella cibaria JW15 Probiotic Antagonistic Antioxidant 



This research was conducted with the financial support of the Cooperative Research Program for Agriculture Science and Technology Development, Rural Development Administration, Republic of Korea (Project No. PJ01254102).

Compliance with ethical standards

Conflict of interest

The authors have declared no conflict of interest.


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Copyright information

© The Korean Society of Food Science and Technology and Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Food Science and Biotechnology of Animal ResourcesKonkuk UniversitySeoulRepublic of Korea
  2. 2.Functional Food and Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural ScienceRural Development AdministrationJeonjuRepublic of Korea
  3. 3.Aram Co., Ltd.GwangjuRepublic of Korea

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