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Food Science and Biotechnology

, Volume 28, Issue 1, pp 215–224 | Cite as

Comparative study on anti-oxidative and anti-inflammatory properties of hydroponic ginseng and soil-cultured ginseng

  • Ji Eun Hwang
  • Dong Hwa Suh
  • Kee-Tae Kim
  • Hyun-Dong PaikEmail author
Article
  • 175 Downloads

Abstract

Hydroponic ginseng (HPG) and soil-cultured ginseng (SCG) were extracted in 70% methanol to quantify relative content of 8 ginsenosides and polyphenolic compounds, and flavonoids to compare their antioxidative effects. Level of nitric oxide and inflammatory targets produced in LPS-stimulated RAW 264.7 cells were measured. 2-year-old HPG shoots contained highest levels of ginsenoside Rb2, Rb3, Rd, Re, and F1. Total polyphenol content was highest in shoots of HPG, followed by roots of HPG and SCG. HPG shoots had high radical scavenging activity and an elevated ability to inhibit linoleic acid oxidation. 2-year-old HPG shoots reduced nitric oxide production in RAW 264.7 cells by 47%, whereas 6-year-old SCG roots reduced it by only 21%. HPG also significantly lowered mRNA expression of iNOS, TNF-α, IL-1β, and IL-6, as determined by RT-PCR, compared to SCGs. Therefore, HPG may have potential for utilization as an alternative to SCG, because of superior antioxidant and anti-inflammatory properties.

Keywords

Hydroponic ginseng Panax ginseng Flavonoid Antioxidative effect Anti-inflammatory effect 

Notes

Acknowledgements

This research was supported by the Priority Research Centers Program through the National Research Foundation of Korea (NFR) funded by the Ministry of Education, Science and Technology (Grant Number: 2009-0093824).

Compliance with ethical standards

Conflict of interest

The authors declared that they have no conflict of interest.

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Copyright information

© The Korean Society of Food Science and Technology and Springer Science+Business Media B.V., part of Springer Nature 2018
corrected publication September 2018

Authors and Affiliations

  1. 1.Department of Food Science and Biotechnology of Animal ResourcesKonkuk UniversitySeoulRepublic of Korea
  2. 2.Bio/Molecular Informatics CenterKonkuk UniversitySeoulRepublic of Korea

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