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Food Science and Biotechnology

, Volume 28, Issue 1, pp 209–214 | Cite as

Antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium from a Jeju water concentrate

  • Ji-Hyun Yun
  • Sung-Hwan Park
  • Goo-Hee Choi
  • In-Jae Park
  • Jin-Ha Lee
  • Ok-Hwan Lee
  • Jung-Hyon Kim
  • Yun-Hee Seo
  • Ju-Hyun ChoEmail author
Article
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Abstract

The purpose of this study was to determine the antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium (BECV). The BECV was prepared following nutriculture of B. napus with a Jeju water vanadium concentrate for 7 day. The BECV was administered to db/db mice for 8 weeks at different dosages (0.028, 0.14, and 0.7 μg/kg; as vanadium concentration in BECV). After 8 weeks, the BECV results showed mouse blood glucose concentrations to significantly decrease, in a dose-dependent manner, compared with the results for control mice. In addition, the concentrations of triglyceride, total cholesterol, and glycated hemoglobin were significantly lower after 8 weeks of administration of 0.7 μg/kg BECV. Therefore, the BECV may have protective effects against type 2 diabetes.

Keywords

Vanadium Brassica napus extract Antidiabetic effect db/db mouse 
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Notes

Acknowledgements

This research was financially supported by the Ministry of Trade, Industry & Energy (MOTIE), Korea Institute for Advancement of Technology (KIAT) and Jeju Institute for Regional Program Evaluation (GWIRPE) through the Leading Industry Development for Economic Region [No. R0000359].

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Copyright information

© The Korean Society of Food Science and Technology and Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Hurum Central Research Institute Co., Ltd.SeogwipoRepublic of Korea
  2. 2.Department of Food Science and BiotechnologyKangwon National UniversityChuncheonRepublic of Korea
  3. 3.Department of Culinary ArtsJeju Tourism UniversityJejuRepublic of Korea
  4. 4.EBO Co., Ltd.CheongjuRepublic of Korea

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