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Effects of a chitosan coating on properties of retinol-encapsulated zein nanoparticles

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Abstract

Zein nanoparticles coated with chitosan were prepared for encapsulation of retinol. The mean particle size of retinol-loaded zein nanoparticles was approximately 300 nm. After coating with chiotsan, the mean particle size increased to >500 nm. The zeta potential of retinol-loaded zein nanoparticles was approximately -30 mV, which was changed to >+24 mV after chitosan coating. The encapsulation efficiency of zein nanoparticles increased from 64.9% to >80% after chitosan coating. The release profile was greatly improved with a chitosan coating, and a slow release rate was observed. FTIR analysis of retinol-loaded chitosan-coated zein nanoaprticles showed cross-linking between zein and retinol through electrostatic interactions. Photochemical stability against UV light was greatly improved to >90% after encapsulation. The concentration of chitosan, the Mw of chitosan, and the zein/chitosan volume ratio were important parameters affecting the properties of nanoparticles.

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Correspondence to Bum-Keun Kim.

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Park, C., Park, D. & Kim, B. Effects of a chitosan coating on properties of retinol-encapsulated zein nanoparticles. Food Sci Biotechnol 24, 1725–1733 (2015). https://doi.org/10.1007/s10068-015-0224-7

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Keywords

  • retinol
  • zein
  • chitosan
  • nanoparticle
  • encapsulation