Food Science and Biotechnology

, Volume 23, Issue 1, pp 157–163

The prebiotic lactosucrose modulates gut metabolites and microbiota in intestinal inflammatory rats

  • Xiaoli Zhou
  • Zheng Ruan
  • Xiaoliu Huang
  • Yan Zhou
  • Shiqiang Liu
  • Yulong Yin
Research Article

DOI: 10.1007/s10068-014-0021-8

Cite this article as:
Zhou, X., Ruan, Z., Huang, X. et al. Food Sci Biotechnol (2014) 23: 157. doi:10.1007/s10068-014-0021-8

Abstract

The effect of lactosucrose on the short chain fatty acid (SCFA) content, the intestinal flora, the acidity, and the amino nitrogen (NH3-N) content of the intestine in inflammatory bowel disease (IBD) rats was investigated. Dietary lactosucose supplementation increased amounts of beneficial bacteria and diminished amounts of pathogenic bacteria. Lactosucrose decreased the NH3-N content in cecal and colonic digesta, compared to inflammatory rats. Lactosucrose increased the acidity in the intestinal lumen, and the acetic acid, propionic acid, and butyric acid contents in cecal and colonic digesta, compared to inflammatory rats. The butyrate content in the lactosucrose group was higher than for the inflammatory, sulfasalazine, and normal groups. Lactosucrose promoted beneficial intestinal health and prevented intestinal inflammation.

Keywords

lactosucrose microflora prebiotic inflammation 

Copyright information

© The Korean Society of Food Science and Technology and Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Xiaoli Zhou
    • 1
    • 2
  • Zheng Ruan
    • 1
  • Xiaoliu Huang
    • 1
  • Yan Zhou
    • 1
  • Shiqiang Liu
    • 1
  • Yulong Yin
    • 1
    • 3
  1. 1.State Key Laboratory of Food Science and Technology, College of Life Science and Food EngineeringNanchang UniversityNanchangChina
  2. 2.College of Food and Pharmacy EngineeringGuiyang UniversityGuiyangChina
  3. 3.Hunan Provincial Engineering Research Center of Healthy Livestock, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical AgricultureChinese Academy of SciencesChangshaChina

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